Senior Analytical Scientist – Analytical Sciences and Technology - Lilly Medicine Foundry
About The Position
Lilly is seeking a Senior Analytical Scientist to join the Analytical Sciences and Technology (ASAT) team at the new Lilly Medicine Foundry. This lab-based role will support synthetic and biologic drug substance processes through various stages, including transfer, scale-up, optimization, and production. The position involves collaborating with CMC development, process engineers, chemists, and other scientists to identify and implement analytical methods and Process Analytical Technology (PAT) tools. The ASAT group focuses on implementing new technologies and improving analytical processes. This role is crucial for establishing a culture of safety, quality, and continuous improvement within the new facility. The Lilly Medicine Foundry is a new center for advanced manufacturing and drug development, combining research and manufacturing to optimize processes, increase capacity, and reduce costs and environmental impact. During the Project Delivery and Startup Phases (2026-2028), roles will be dynamic, requiring collaboration, creativity, and resilience.
Requirements
- B.S. in Chemistry, Analytical Chemistry, Chemical Engineering, Biochemistry, Biophysics, Pharmaceutical Science, or a closely related STEM field, with at least 8 years of experience in analytical characterization using chromatographic systems coupled with various detectors; or an M.S. with at least 5 years of relevant analytical characterization experience.
- Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role.
Nice To Haves
- Extensive experience with analytical techniques, including but not limited to HPLC/UPLC, GC, LC-MS/LC-HRMS, and spectroscopic methods (e.g., NIR, Raman, UV/Vis, FTIR), used for the chemical and/or physical characterization of synthetic and biologic drug substance.
- Hands-on experience developing and validating analytical methods for synthetic and biologic drug substance, including method transfer into GMP manufacturing or QC operations.
- Demonstrated experience supporting pharmaceutical development, with a proven track record of transitioning analytical methods from development into manufacturing and commercial testing environments.
- Demonstrated ability to drive and embrace change in a dynamic environment.
- Good interpersonal skills and a sustained tendency for collaboration.
- Demonstrated success in persuasion, influence, and negotiation.
- Ability to prioritize multiple activities and manage ambiguity.
- Strong communication (oral, written), organizational, and leadership skills.
- Working knowledge of cGMP compliance requirements, with direct cGMP experience.
Responsibilities
- Transfer analytical methods from Product Research and Development laboratories, refining test methods for robustness, accuracy, and precision according to ICH guidelines.
- Drive the implementation of technical solutions and analytical/PAT strategies at the Lilly Medicine Foundry for diverse drug substance production (synthetic molecules, bioconjugates, biologics), utilizing both off-line laboratory testing and in-line/on-line PAT.
- Demonstrate high learning agility and the ability to understand and apply scientific concepts across chemistry, engineering, analytical sciences, and data sciences.
- Plan and manage short-term and long-term development activities, including developing technical agendas, timelines, recommending resource allocation, communicating progress, and proposing changes.
- Collaborate with development and manufacturing organizations to provide material and information for clinical trials and regulatory submissions.
- Serve as a subject matter expert (SME) and technical mentor for team members, providing guidance on experimental design, data interpretation, and problem-solving.
- Welcome varied perspectives to create new solutions.
- Coordinate instrumentation across projects to ensure equal usage of available tools.
- Author, review, or approve technical documents such as SOPs, batch records, technology transfer reports, deviation reports, process flow diagrams, regulatory submissions, patents, and scientific papers.
- Present technical findings and project updates clearly to the ASAT group and cross-functional teams.
- Ensure work and team activities align with development, quality, regulatory, HSE, GLP, and GMP requirements.
Benefits
- company bonus (depending, in part, on company and individual performance)
- company-sponsored 401(k)
- pension
- vacation benefits
- medical benefits
- dental benefits
- vision benefits
- prescription drug benefits
- flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
- life insurance
- death benefits
- certain time off and leave of absence benefits
- well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)
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What This Job Offers
Job Type
Full-time
Career Level
Senior
