Scientist, Stem Cell Engineering

Colossal • Dallas, TX

3d • Onsite

About The Position

An affiliate of Colossal Biosciences is seeking a stem cell biologist interested in manipulating avian embryonic stem cells. The Scientist will work with other laboratory team members to develop and improve protocols for avian stem cell culture, genome editing, and reintroduction into embryos using advanced technologies. The position is based in Dallas, Texas, and relocation assistance is available.

The role involves culturing and characterizing avian embryonic stem cells, deriving cultures from avian embryos, injecting stem cells into avian blastodiscs, and working with the team to assess genome-editing efficiency. The Scientist also participates in lab meetings and prepares project progress reports and presentations.

Requirements

• PhD in biological sciences, cell biology, bioengineering, molecular biology, genetics, or a related science field.
• Experience with embryonic stem cell cultures.
• Experience manipulating embryos under a microscope.
• Experience in cell line derivation, culture, propagation, and transfection methodologies.
• Experience in molecular biology, including nucleic acid and protein extraction and gel electrophoresis.
• Experience with flow cytometry, immunostaining, and cell microscopy.
• Strong written and oral communication skills.
• Creative problem-solving skills.

Responsibilities

• Culture avian embryonic stem cells and test novel cell culture conditions.
• Transfect cells, sort monoclonal cell lines, and screen and expand cells using current protocols and newly developed approaches.
• Collect avian blastodiscs from embryos using a dissection microscope and derive stem cell cultures.
• Characterize and perform quality control on avian stem cell cultures.
• Inject stem cells into avian blastodiscs.
• Work with team members to assess editing efficiency using next-generation sequencing approaches.
• Attend lab meetings and prepare reports and presentations on project progress.
• Maintain excellent organization and laboratory records.

Benefits

• Relocation assistance.
• Medical, dental, and vision coverage.
• Paid time off and company holidays.
• Flexible spending accounts (FSA).
• Company-matched 401(k) retirement plan.
• Paid parental leave at 100% salary for up to 12 weeks.
• Education reimbursement.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree