Scientist/Sr. Scientist - Microdialysis

PsychoGenics Inc.•Paramus, NJ

About The Position

PsychoGenics is a preclinical CRO with expertise in central nervous system (CNS) and orphan disorders. Our mission is to provide the best validated disease models and comprehensive preclinical capabilities to help companies discover the next generation of treatments for severely disabling CNS and orphan disorders and reduce the attrition rate in clinical development. We are known for our cutting-edge translational approach to research, our customized solutions, the breadth, and quality of our work, as well as for our ability to identify statistically relevant phenotypic changes that help our clients quantify the efficacy of their treatments before they move into the clinic. With an extensive portfolio of highly predictive disease models and unparalleled experience performing studies for biopharmaceutical companies of all sizes, we enable clients to deliver much needed superior clinical candidates to patients. We are seeking a Research Scientist to fill a Study Director role in our CNS focused contract research organization (CRO). We are seeking an expert on pre-clinical microdialysis that has a background in using microdialysis techniques in rodents. This position will work closely with the VP, Translational Neuroscience and the Associate Director of the EEG Group to lead studies that collect microdialysis samples following various experimental protocols including administration of novel test articles and genetic manipulations. Studies performed at PsychoGenics include single and dual probe experiments in mice and rats. Microdialysis techniques include standard microdialysis, push-pull microdialysis for large molecules, retro dialysis, and quantitative microdialysis. Studies investigate levels of neurotransmitters, novel compounds, and large molecules such as antibodies or a-synuclein. The ideal candidate will be an expert pre-clinical rodent microdialysis with a knowledge of basic sleep science. Being able to thrive in a busy, fast-paced work environment is a must as is working in collaboration with other scientists on the team. This position will also lead junior staff members.

Requirements

Previous management/supervisory experience.
PhD in Neuroscience, Biomedical Engineering, or other related degree.
3-10 years of demonstrated applicable microdialysis experience.
Experience with standard, push-pull, retro, and quantitative microdialysis techniques.
Ability to interact appropriately with all levels of management/employees and work effectively as a member of a team.
Ability to simultaneously manage multiple responsibilities and priorities.
Demonstrated independent analytical and problem-solving abilities.

Nice To Haves

Prior experience in a Contract Research Organization (CRO) and/or Drug Discovery environment.
Previous success as a team leader and motivator, with excellent verbal and written communication and organizational skills.
Programming experience (i.e., Matlab, EEGLAB, Python, R, and/or statistical software like SAS).

Responsibilities

Rapidly gain expertise in all procedures and techniques used by the microdialysis team.
Work and manage all levels of personnel in a positive, respectful manner.
Ability to train staff and help nurture their careers.
In coordination with management, design and develop experiments that use microdialysis techniques following pharmaceutical agents and/or genetic manipulations.
Perform, manage, and oversee studies, including surgeries, dosing, QC'ing, and coordination with the PGI bioanalysis team when applicable.
Work with management to help write study plans and reports and be able to discuss the data collection and analyses process in a clear manner.
Will have some engagement with clients on study design and reporting of data.
Ability to process data (Prism) and create clear and concise data presentations.
Maintenance and troubleshooting of the microdialysis equipment.