iPSC Research–Foster City, CA (San Francisco Bay Area)

Illumina•Foster City, CA

2d•$113,300 - $169,900•Onsite

About The Position

Illumina is seeking a highly motivated and talented experimental scientist to lead a multi-disciplinary project focused on the experimental validation of novel drug targets identified from human genetics, utilizing human iPSC systems. This role is part of an initiative to leverage Illumina's leadership in human genetic data to pursue a unique human genetics-first approach to target discovery. The successful candidate will work collaboratively with a multidisciplinary team of experimental scientists, statistical geneticists, and deep learning engineers to validate therapeutic hypotheses. This is an opportunity to design, plan, and execute experiments in the lab to support early discovery efforts, employing novel approaches to study various disease indications using high-throughput functional genomics strategies in human iPSC systems, with a focus on identifying and validating therapeutic targets and next-generation biomarkers.

Requirements

Minimum 2 years experience in a laboratory technician / research associate role (for Scientist 1/2).
Extensive expertise with genetic molecular biology techniques, with particular emphasis on development of iPSC models, primary cell culture, high-throughput sequencing assays, CRISPR, single cell sequencing, target identification, and target validation.
Strong record of technical proficiency, innovation, and scientific rigor as demonstrated by publication in high-quality scientific journals.

Responsibilities

Lead the development of cutting-edge techniques and systems for running high-throughput sequencing experiments on iPSC-derived cell types and systems.
Design, develop and validate quantitative cellular assays to credential novel targets.
Lead academic and clinical collaborators to integrate innovative biology with data from large-scale human genetics and high throughput sequencing assays to develop new target hypotheses.
Lead the scientific strategy of the research team.
Present results at scientific meetings and publish in peer-reviewed scientific journals.