iPSC Research–Foster City, CA (San Francisco Bay Area)

Illumina•Foster City, CA

16h•Onsite

About The Position

Illumina is seeking a highly motivated and talented experimental scientist to lead a multi-disciplinary project working on experimental validation of novel drug targets directly identified from human genetics, using human IPSC systems. Illumina’s leadership position in the generation and analysis of human genetic data enables us to pursue a unique human genetics-first approach to target discovery, supported by a multidisciplinary team of dedicated experimental scientists, statistical geneticists, and deep learning engineers working collaboratively to validate therapeutic hypotheses. We are looking for a highly innovative wet lab scientist to design, plan, and execute experiments in the laboratory in support of these early discovery efforts. The successful candidate is expected to pursue novel approaches to study a broad range of different disease indications using high throughput functional genomics strategies in a variety of human IPSC systems, with a focus on identification and validation of therapeutic targets and next-generation biomarkers.

Requirements

Minimum 2 years experience in a laboratory technician / research associate role.
Extensive expertise with genetic molecular biology techniques, with particular emphasis on development of iPSC models, primary cell culture, high-throughput sequencing assays, CRISPR, single cell sequencing, target identification, and target validation.
Strong record of technical proficiency, innovation, and scientific rigor as demonstrated by publication in high-quality scientific journals.

Responsibilities

Lead the development of cutting-edge techniques and systems for running high-throughput sequencing experiments on IPSC-derived cell types and systems.
Design, develop and validate quantitative cellular assays to credential novel targets.
Lead academic and clinical collaborators to integrate innovative biology with data from large-scale human genetics and high throughput sequencing assays to develop new target hypotheses.
Responsibility to lead the scientific strategy of the research team.
Present results at scientific meetings and publish in peer-reviewed scientific journals.