Scientist – LNP Formulation

Thermo Fisher Scientific•Boston, MA
•Onsite

About The Position

Thermo Fisher Scientific is hiring an onsite Scientist – LNP Formulation to support its Laboratories Functional Service Partnership team at a customer site in Boston, Massachusetts. The team provides long-term laboratory support within customer organizations to advance drug development. The role focuses on manufacturing small- and large-scale lipid nanoparticle (LNP) formulations, including production, purification, and analysis using industry-standard protocols. The scientist is expected to meet deadlines, maintain complete electronic laboratory notebook records, follow SOPs, and adapt to a fast-paced drug development environment while collaborating with a team and developing new technical capabilities. The position is full-time, onsite, Monday through Friday, 8:00 a.m.–5:00 p.m. EST. Applicants must be legally authorized to work in the United States without sponsorship and pass a comprehensive background check, including drug screening. Applicants may be located anywhere in the United States, but relocation assistance is not provided.

Requirements

  • Bachelor's degree in a laboratory science such as Chemistry, Biochemistry, Material Science, Immunology, Biology, Molecular Biology, or a similar field.
  • For the Scientist level, comparable experience providing the knowledge, skills, and abilities to perform the role, typically 2 or more years, or a master's degree.
  • Hands-on experience with LNP formation mixing technologies, including microfluidic mixing and Impingement Jet Mixing devices.
  • Hands-on experience and knowledge of LNP purification techniques, including tangential flow filtration (TFF).
  • Hands-on experience conducting LNP process development experiments focused on maintaining product quality.
  • Experience manufacturing LNP formulations for non-human primate studies.
  • Knowledge and experience with LNP analytics, including size, PDI, RNA encapsulation, osmolality, and endotoxin measurement.
  • Exemplary work ethic and commitment to scientific rigor.
  • Strong communication skills.
  • Ability to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
  • Ability to work upright and stationary and/or standing for typical working hours.
  • Ability to lift and move objects weighing up to 25 pounds.
  • Ability to work in non-traditional work environments and use and learn standard office equipment and technology proficiently.
  • Ability to perform successfully under pressure while prioritizing and handling multiple projects or activities.
  • Legal authorization to work in the United States without sponsorship.
  • Ability to pass a comprehensive background check, including drug screening.

Responsibilities

  • Manufacture small- and large-scale LNP formulations, including production, purification, and analysis, using industry-standard protocols.
  • Meet established deadlines.
  • Maintain clear and complete experimental records in an electronic laboratory notebook (ELN).
  • Follow SOPs and generate and maintain thorough, accurate documentation.
  • Adapt to strategic changes in a dynamic, fast-paced drug development environment.
  • Learn new techniques and expand technical capabilities.
  • Collaborate effectively within a team.

Benefits

  • Competitive remuneration
  • Annual incentive plan bonus, potentially based on company, team, and/or individual performance results in accordance with company policy
  • National medical and dental plans and a national vision plan, including health incentive programs
  • Employee assistance and family support programs
  • Commuter benefits
  • Tuition reimbursement
  • At least 120 hours of paid time off (PTO)
  • 10 paid holidays annually
  • Paid parental leave, including 3 weeks for bonding and 8 weeks for caregiver leave
  • Accident and life insurance
  • Short- and long-term disability in accordance with company policy
  • Competitive 401(k) U.S. retirement savings plan
  • Employees’ Stock Purchase Plan (ESPP), with eligible colleagues able to purchase company stock at a discount
  • Career and development prospects
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