Scientist II/Senior Scientist I, InVitro Pharmacology

Zealand Pharma • Cambridge, MA

3d

About The Position

As a Scientist II / Senior Scientist I in In Vitro Pharmacology, you will design, execute, and interpret biochemical, biophysical, and cell-based functional assays across obesity, diabetes, and broader metabolism programs. The role is hands-on at the bench and supports lab automation and workcells, assay innovation, high-throughput screening, and LIMS integration. You will collaborate with Research AI, Chemistry, in vivo Pharmacology, DMPK/Safety, and Formulation colleagues to help advance candidates with pharmacological properties suited to clinical success. The position also offers the opportunity to help build automation-ready, high-throughput in vitro pharmacology capabilities.

You will join the Global Biology research organization, working at the interface of discovery and preclinical candidate delivery. The team contributes robust in vitro data generation and interpretation to a portfolio of programs and collaborates with functional experts across the organization.

Requirements

• Ph.D. in Pharmacology, Biology, Biochemistry, Cell Biology, or a related field with 0–3 years of relevant industry or postdoctoral experience; M.S. with approximately 3–6 years of relevant industry experience; or B.S./B.A. with approximately 5–8+ years of relevant industry experience.
• Strong hands-on experience in in vitro pharmacology and cell-based assay development.
• Experience with GPCR pharmacology and associated assay formats.
• Experience working with biologics, including antibodies, proteins, peptides, and bioconjugates.
• Strong data analysis, interpretation, and scientific communication skills.
• An innovative mindset, a strong publication or project track record, clear communication, and the ability to collaborate across disciplines.

Nice To Haves

• Experience with GPCR pharmacology in obesity, diabetes, or broader metabolic disease research.
• Experience in lab automation, Research AI, custom coding, and/or workcell environments.
• Exceptional candidates at any degree level with expertise and a track record that are an outstanding match for the role may be considered for Senior Scientist I.

Responsibilities

• Support the building and implementation of automation integrating tissue culture, liquid handling, and plate readers or microscopes.
• Design, optimize, and validate biochemical, biophysical, and cell-based assays for compound screening and mechanism-of-action studies.
• Generate, analyze, and clearly communicate pharmacological data to enable timely, high-quality decisions across discovery programs.
• Represent In Vitro Pharmacology in cross-functional teams.
• Maintain rigorous documentation and contribute to a strong culture of data quality and scientific integrity.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level