Scientist II – Oligonuleotide Synthesis
Dawar Consulting•South San Francisco, CA
•Onsite
About The Position
Our client, a world leader in biotechnology and gene therapy, is looking for an “Scientist II – Oligonuleotide Synthesis” based in South San Francisco, CA. This role focuses on oligonucleotide therapeutics discovery, supporting RNAi-based research through synthesis, characterization, and collaboration across therapeutic areas.
Requirements
- BS/MS in Organic Chemistry or related field.
- Hands-on experience with oligonucleotide synthesis, purification, and characterization.
- Experience with automated oligo synthesizers, HPLC, and mass spectrometry.
Nice To Haves
- Understanding of RNAi, nucleic acid therapeutics, and modification chemistries preferred.
- Industry experience in biotech/pharma R&D is a plus.
Responsibilities
- Design and execute oligonucleotide synthesis and purification workflows.
- Perform HPLC and mass spectrometry analysis for characterization and impurity profiling.
- Support RNAi and nucleic acid therapeutic discovery across neuroscience, immunology, and oncology programs.
- Develop and scale up synthesis of lead oligonucleotide candidates for preclinical studies.
- Collaborate with cross-functional teams to integrate chemistry and biology data.
- Maintain and troubleshoot lab equipment (e.g., oligo synthesizers, HPLC systems).
- Conduct literature reviews and contribute to experimental design and strategy.
Benefits
- Medical
- Dental
- Vision
- Paid Sick leave
- 401K
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
Associate degree
