Scientist II, Immunology

Vaxart•South San Francisco, CA

2d•$130,000 - $150,000•Onsite

About The Position

Vaxart is seeking a highly motivated Scientist I/II to join its Immunology team in South San Francisco. This onsite role leads clinical and preclinical immunology studies supporting the advancement of Vaxart’s mucosal vaccine platform and generates data to inform research and development decisions. The scientist designs, optimizes, executes, and analyzes cellular and humoral immunology assays and ex vivo immune profiling studies using human PBMCs and other clinical samples. The role also manages preclinical studies, develops laboratory methods and SOPs, maintains rigorous experimental records, and collaborates with Research and Clinical teams. The scientist contributes to scientific and regulatory materials and presents findings and recommendations to multidisciplinary teams.

Requirements

PhD in Immunology, Cell Biology, or a relevant discipline.
Strong understanding of cellular immunology and humoral responses, particularly in infectious disease and/or vaccination.
Extensive experience designing, executing, and interpreting multiparameter flow cytometry.
Strong understanding of human immune cell immunophenotyping and functional assays, including activation-induced marker (AIM) and memory T cell analysis.
Proficiency with FlowJo, GraphPad Prism, and Microsoft Office software.
Excellent written and verbal communication skills, including experience presenting scientific data to diverse audiences.
Strong interpersonal communication and organization skills, with exceptional attention to detail.
Ability to work onsite at the laboratory in South San Francisco, California.

Nice To Haves

Experience working with clinical samples in a regulated or industry environment.

Responsibilities

Independently design, optimize, execute, and analyze cellular and humoral immunology assays, including multiparameter flow cytometry (10+ colors), MesoScale Discovery (MSD), and neutralization assays using human biospecimens.
Design and optimize ex vivo immune profiling studies using human PBMCs and other clinical samples.
Lead and manage external and internal in-vitro and in-vivo preclinical studies.
Develop and optimize laboratory methods and standard operating procedures (SOPs).
Maintain detailed experimental records and ensure data integrity and reproducibility.
Collaborate cross-functionally with Research and Clinical teams to achieve project goals.
Contribute to scientific publications, regulatory documents, and grant applications.
Present scientific findings, project updates, and strategic recommendations to multidisciplinary teams.