Scientist I/II, Bioanalytical (LC-MS)
About The Position
We are seeking a highly motivated bioanalytical scientist to fulfil a Scientist role in our DMPK group. The candidate will be responsible for developing and employing LC-MS methods to characterize and quantitate proteins, oligos and lipid in cells, blood and tissues to support discovery, preclinical, and clinical programs for a variety of therapeutic indications. The ideal candidate must have excellent communication skills and is willing to work in a highly dynamic and fast-paced work. Tessera employees are creative and collaborative problem solvers. They have a strong sense of integrity and unwavering commitment to scientific excellence.
Requirements
- PhD in Analytical Chemistry or related discipline e.g., Biochemistry, Biotechnology or Pharmaceutical Science, with 0-3 years of industry experience in biotech, pharmaceutical, and/or CROs.
- Hands-on Experience in LC-MS based bioanalysis of proteins, oligos or small molecules in biological matrix is required.
- In-depth scientific knowledge and hands on technical expertise on LC-MS, LC-MS/MS, and chromatography methodologies and instrumentation is required.
- Proficiency of using Sciex Triple Quadrupole LC-MS/MS system or Thermo Orbitrap mass spectrometers such as Q Exactive series or Exploris series.
Nice To Haves
- Postdoc experience is a plus.
- Experience with lab automation technologies is a plus.
Responsibilities
- Develop, optimize, and validate bioanalytical methods to measure proteins, oligos, and lipids in biological samples, including cells, biofluids, and tissues, to support the development of discovery, preclinical and clinical programs.
- Design and execute experiments from sample preparation, LC-MS/MS operation to data analysis & interpretation.
- Guide CROs for method transfer CROs and serve as technical expert for method trouble shooting.
- Write internal assay protocols, ROPs, qualification plans, and sample analysis reports.
- Provide maintenance, quality control and troubleshooting of LC-MS systems.
Benefits
- group medical, vision, and dental coverage
- group life and disability insurance
- a 401(k) plan with company contribution
- tuition reimbursement
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
Ph.D. or professional degree
