Scientist I, Compound Management

Valo Health•Lexington, MA

16h•$110,500 - $130,000

About The Position

Valo Health is seeking a Scientist I to join the Compound Management team, supporting the day-to-day operations of compound handling, registration, and distribution across its drug discovery organization. This is a hands-on laboratory role for a detail-oriented, resourceful scientist with strong experience in compound management automation and a continuous improvement mindset. The successful candidate will work cross-functionally with IVP, ADME, chemistry, and DEL technology teams to ensure compounds are accurately tracked, prepared, and delivered to support Valo’s scientific functions.

Requirements

Entry-level PhD in a relevant scientific discipline (e.g., biology, chemistry, pharmacology, bioengineering, informatics) (or equivalent education and experience, including postdoctoral training),
minimum of 5 years in compound management.
Resourceful and highly organized, with a detail-oriented approach to planning and executing at the bench; ability to manage multiple priorities concurrently.
Experience operating and troubleshooting compound management automation platforms, liquid handling, acoustic dispensation, and periphery devices (tube sorting, 2D barcode scanning).
Experience with sample storage systems and integrations with liquid handlers and automation systems.
Ability to work independently and cross-functionally with IVP, ADME, and chemistry teams in a collaborative, dynamic environment; strong commitment to inventory control, accurate recordkeeping, and audit readiness.
Continuous improvement mindset with a track record of identifying efficiencies and contributing to process development.
Strong written and verbal communication skills; comfortable contributing to scientific discussions and cross-functional planning.

Nice To Haves

Liquid handling scripting, workflow scheduling, and software programming are strong pluses; experience with Titian Mosaic and Dotmatics LIMS is a plus.

Responsibilities

Execute compound management workflows including compound registration, weighing, stock solution reformatting, inventory curation, liquid-liquid plate transfers, and archive storage.
Partner with IVP, ADME, chemistry, and biology teams to coordinate compound activities and deliver assay-ready plates in support of rapid DMTA cycles and HTS campaigns.
Maintain consumable supplies; author and maintain SOPs, protocols, and inventory records to ensure data integrity, accurate audit trails, and operational continuity.
Interface with CROs and vendors for external compound inventories, purchasable compound orders, and shipments; support service contract coordination and vendor troubleshooting.
Work with chemistry and DEL technology teams to curate and manage the chemical building block inventory, ensuring accurate registration, stock integrity, and alignment with program needs.
Design and enable new plating workflows to support IVP and ADME science teams; troubleshoot automation and software platforms and integrate novel workflows as needs evolve.
Stay current with industry trends in compound management and liquid handling; propose and build the case for adoption of new technologies and workflow improvements.