Scientist I, Bioanalytical

Maze Therapeutics•South San Francisco, CA

6d•$130,000 - $159,000•Hybrid

About The Position

We are seeking a detail-oriented Scientist to work in the Non-Clinical Development department overseeing bioanalytical work for Maze. In this role, you will oversee bioanalysis for Good Laboratory Practices (GLP), Good Clinical Laboratory Practices (GCLP), and non-GLP studies in support of the development of small molecule drugs. As part of the Non-Clinical Development team, you will have the opportunity to contribute to key drug discovery and development projects.

Requirements

Bachelor’s degree in analytical chemistry, chemistry, biochemistry, or related field.
6+ years of relevant experience, ideally within a pharmaceutical company, a CRO, or academia, with a focus on bioanalysis oversight.
Experience and understanding of GLP and GCLP principles and guidances
Experience in GLP and GCLP analysis of one or more bioanalytical techniques, including: LC-MS/MS, ELISA, and MSD
Experience working with multidisciplinary project teams, driving successful outcomes.
Ability to manage multiple projects simultaneously with excellent attention to detail.
Clear and effective communication skills to present complex scientific information to various stakeholders.

Responsibilities

Oversee the development, validation, and execution of bioanalytical assays for both pharmacokinetics and pharmacodynamics for ongoing preclinical, nonclinical, and clinical programs.
Manage the collaborations with contractor laboratories conducting bioanalysis and review data from analysis to confirm analyses were correctly conducted and batch analyses met acceptance criteria.
Provide written summaries of bioanalytical methods for regulatory submissions as needed.
Coordinate regulated bioanalysis activities across development programs, ensuring compliance with timelines and regulatory standards.
Provide timeline updates to the Head of Bioanalysis, Nonclinical Development, and collaborate with key stakeholders in Research, Regulatory Affairs, Manufacturing, Quality, and Clinical Sciences to address bioanalysis-related project issues.
Review, investigate, and coordinate resolution of study queries with contract research organization (CRO) and personnel regarding data integrity.