Scientist, Antibody Discovery

Systimmune • Alderwood Manor, WA

16h • $90,000 - $115,000

About The Position

SystImmune is seeking a highly skilled and motivated Scientist to join its Antibody Discovery Group. The role advances antibody discovery efforts through immunogen design, B-cell sorting, flow cytometry, ELISA, and yeast library screening. The successful candidate will work in a dynamic, innovative environment focused on developing novel therapeutic antibodies, and will collaborate with cross-functional teams on project planning and strategy.

Requirements

• Ph.D. in Immunology, Molecular Biology, Biochemistry, or a related field.
• 0–2 years of industry experience.
• 3–7 years of hands-on experience in B-cell sorting and screening through flow cytometry, ELISA, and bio-layer interferometry.
• Proficiency in flow cytometry and cell-sorting techniques.
• Experience with biolayer interferometry assays, including affinity, avidity, and binning, or similar assays.
• Strong background in ELISA assay development and optimization.

Nice To Haves

• A proven track record of working with Sony cell sorters or similar instruments.
• Experience with single-cell analysis platforms such as Beacon.
• Experience in antibody discovery and development.
• Experience in NGS library preparation and BCR repertoire analysis.
• Expertise in molecular biology techniques related to yeast display libraries, including preparation, culture, and screening.

Responsibilities

• Design and execute antibody discovery campaigns from immunization through lead delivery.
• Perform high-throughput sorting to isolate specific B-cell populations.
• Design, execute, and analyze FACS experiments to validate and characterize antibodies.
• Develop, optimize, and perform ELISA, BLI, and flow cytometry assays for antibody screening and specificity testing.
• Conduct yeast display library screening to identify and analyze antibody candidates.
• Analyze experimental data and prepare detailed reports and presentations.
• Work with cross-functional teams and contribute to project planning and strategy.
• Maintain accurate records, ensure safety compliance, and contribute to laboratory organization.

Benefits

• 100% paid employee premiums for medical, dental, and vision coverage.
• Short-term disability (STD) coverage.
• Long-term disability (LTD) coverage.
• 401(k) plan with a 50% company match of up to 3%, and a five-year vesting schedule.
• 15 PTO days per year.
• Sick leave.
• 11 paid holidays.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree