Scientist 4, Translational Medicine

GenentechDaly City, CA
$124,800 - $231,800Onsite

About The Position

Genentech's Translational Medicine OMNI (TM OMNI) Department supports the entire R&D portfolio of novel therapies in Ophthalmology, Metabolism, Neuroscience, Immunology, and Infectious Diseases (OMNI). We develop and implement biomarker strategies to study disease pathways, confirm a therapeutic's mechanism of action, and improve clinical trial efficiency and success. Additionally, we lead reverse translation efforts, leveraging clinical data to support target discovery. The Opportunity: We are seeking a talented and highly motivated Scientist 4 to join Genentech’s Translational Medicine (TM) team on-site at our South San Francisco campus. The candidate will collaborate with scientists across R&D to provide biomarker support for ophthalmology programs across different stages of drug development while also generating insights for the next generation of ophthalmology drug targets. The role will cover: 1) Analysis and interpretation of large-scale -omics datasets from clinical and preclinical studies to enable biomarker discovery and reverse translation; 2) Assay development to support biomarker assessment in clinical and preclinical studies.

Requirements

  • A PhD degree in Biological Sciences with 7+ years of relevant experience.
  • Both wet lab skills and bioinformatics experience are required.
  • A strong record of high-impact publications.
  • Excellent teamwork, communication, time management, organization skills, and ability to work independently.
  • Excellent oral and written presentation skills, creative problem-solving abilities, and a passion for drug discovery and development.

Nice To Haves

  • Industry experience is preferred.

Responsibilities

  • Analyze large scale -omics datasets (proteomics, lipidomics, transcriptomics) generated from clinical and preclinical sample testing.
  • Discover candidate targets based on interpretation of -omics data and a deep understanding of disease biology.
  • Develop, qualify, and validate custom immunoassays (e.g., ELISA, Simoa, NULISA) against biomarkers of interest to support pipeline programs (goes beyond running commercial assay kits).
  • Clearly and concisely communicate findings internally and externally through written reports, publications, and presentations.
  • Coordinate interdepartmental and external collaborations.

Benefits

  • A discretionary annual bonus may be available based on individual and Company performance.

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What This Job Offers

Job Type

Full-time

Career Level

Senior

Education Level

Ph.D. or professional degree

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