Director, Translational Medicine
About The Position
Crescent Biopharma’s vision is to build a world leading oncology company bringing the next wave of therapies for cancer patients. The Company’s clinical-stage pipeline includes its lead program, a PD-1 x VEGF bispecific antibody, as well as novel antibody-drug conjugates. By leveraging multiple modalities and established targets, Crescent aims to rapidly advance potentially transformative therapies either as single agents or as part of combination regimens to treat a range of solid tumors. We are seeking a Director of Translational Medicine to join our team. You will provide scientific and strategic leadership for one or more programs supporting the advancement of Crescent ‘s pipeline focusing on next generation immuno-oncology (I/O) and antibody-drug conjugate (ADC). Working with cross-functional teams, you will develop and execute the Translational Medicine strategy to help shape the clinical development plans and contribute to clinical and scientific deliverables.
Requirements
- PhD/MD in Cancer Biology, Immuno-Oncology, Immunology, Molecular Biology, Pathology, or other scientifically related field required
- Minimum 8 years of industry experience in translational medicine and clinical biomarkers
- Experience in leading translational efforts to advance the IO and/or ADC programs from IND-enabling phase through early phase clinical development and/or from early phase clinical development through late phase
- Strong team player with the ability to work in cross-functional matrix
- Excellent interpersonal, verbal, and written communication skills
Nice To Haves
- Prior experience in CDx development is a plus
Responsibilities
- Develop and execute translational strategy to help advance Crescent’s clinical pipeline
- Provide oversight of the development, validation, and execution of fit-for-purpose clinical biomarker assays with external CROs and actively manage vendor relationships
- Drive clinical biomarker sample testing and data delivery in close collaboration with clinical development operations team
- Lead biomarker data analysis and contribute to clinical and scientific data deliverables
- Serve as the translational medicine lead in cross-functional program teams and support integrated program development plans
- Author translational medicine sections in IND modules, clinical protocols, IBs, ICFs, and other clinical documents and technical reports, and respond to regulatory inquiries related to translational medicine
- Provide translational input into novel target identification
Benefits
- Competitive compensation, including base salary, performance bonus, and equity
- 100% employer-paid benefits package
- Flexible PTO
- Two, one-week company-wide shutdowns each year
- A commitment to your professional development, with access to resources, mentorship, and growth opportunities
- medical, dental, vision, life insurance, short- and long-term disability
- savings plan (401(k))
- long-term incentive program
- Vacation – Unlimited PTO
- Sick time – 10 days per calendar year
- Holiday pay, including two Company shut downs
- Parental Leave – 16 weeks within one year of the birth/adoption/foster care of a child
- FMLA
- Military Leave
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What This Job Offers
Job Type
Full-time
Career Level
Director
Education Level
Ph.D. or professional degree
