Scientist 2, Translational CVRM

Roche•South San Francisco, CA

6d•$85,500 - $158,700•Onsite

About The Position

The CVRM (Cardiovascular, Renal, and Metabolism) Translational Biology group within Genentech Research and Early Development (gRED) is seeking a highly motivated and well-trained individual to advance drug discovery research and development efforts by executing in vivo experiments in rodent models of cardiometabolic diseases. This position requires working closely with scientists in a multidisciplinary team. Our environment is exciting and fast paced, requiring you to be excellent at multitasking and easily adaptable to meet evolving goals. This is an exciting opportunity to join a growing CVRM biology group and make significant contributions.

Requirements

Bachelor’s degree in pharmacology, biology, or related fields with 6+ years of laboratory experience, OR a Master’s degree with 4+ years of experience in industry or academia
A detail-oriented researcher who is passionate about leveraging best disease modeling to accelerate our research and discovery
Hands-on experience with cardiovascular models (myocardial infarction/ischemia–reperfusion, transverse aortic constriction) and their phenotyping (echocardiography, heart catheterization). Proficient survival surgical skills in rodents
Experience with rodent handling, various routes of drug administration (intravenous, intraperitoneal, intramuscular and subcutaneous), non-terminal and terminal blood sampling and tissue harvest.
Strong analytical, organizational and communication skills
Highly motivated, self-driven person, comfortable working independently or as team in a fast-paced environment
Willingness to learn new skills and rapidly adapt to changing priorities for multiple projects.

Nice To Haves

Experience with other cardiometabolic disease models will be a plus.

Responsibilities

Establish and conduct experiments in relevant rodent models and optimize approaches to model disease processes and states which resemble human diseases
Generate high-quality experimental data to meet strict timelines and project goals.
Communicate key findings at project meetings and make recommendations for follow-up studies and prioritization.
Familiar with relevant scientific literature. Understand and apply relevant scientific knowledge to solving problems arising from the projects involved
Work collaboratively within multidisciplinary project teams
Generate, analyze, and document complex experimental data with a focus on high reproducibility, maintaining accurate Electronic Lab Notebook (ELN) records.