Scientist I, Translational Medicine

AbelZeta Inc • Rockville, MD

5d • $60,000 - $85,000 • Onsite

About The Position

AbelZeta is a clinical stage biopharmaceutical company focused on the development of novel immunotherapy products. We are on a rapid growth trajectory and have a highly energized and accomplished team driving to new frontiers of care for cancer and autoimmune disease patients. We are seeking a highly motivated and dynamic Scientist I to join our Translational Medicine team in Rockville, MD. The Translational Medicine team focuses on the analysis of clinical samples to characterize the pharmacokinetic/pharmacodynamic (PK/PD) and biomarker profiles of AbelZeta’s innovative cell therapy products and to better understand the mechanisms associated with treatment response and resistance. As a member of our team, you will contribute to the development, execution, and analysis of translational and clinical bioanalytical assays supporting AbelZeta’s clinical development programs in hematologic malignancies, solid tumors, and autoimmune diseases. You will play an important role in generating high-quality biomarker data and will work closely with internal scientists, cross-functional teams, and external laboratories or partners. The position is primarily laboratory-based and requires strong technical skills, attention to detail, and the ability to work effectively in a fast-paced and collaborative environment.

Requirements

• BS or MS degree in immunology, biology, molecular biology, biomedical sciences, biotechnology, or a related scientific discipline (MS preferred).
• Relevant laboratory experience in biotechnology, biopharmaceutical research, translational medicine, or a related field.
• Strong technical skills, attention to detail, and the ability to work effectively in a fast-paced and collaborative environment.
• Hands-on experiences with cell culture, qPCR, and FACS are strongly preferred.
• Experience with ELISA or other ligand-binding assays is desirable.
• Strong attention to detail and ability to maintain accurate and complete experimental documentation.
• Excellent oral and written communication skills, attention to detail, able to document work clearly, concisely, and understand and describe its importance to others.
• Strong organizational and time-management skills, with the ability to prioritize and manage multiple activities while meeting established timelines and quality expectations.
• Good interpersonal skills – able to work effectively with colleagues/collaborators from diverse backgrounds, levels of seniority, and territories.
• Demonstrated willingness and ability to learn new technologies, assays, and scientific concepts.

Nice To Haves

• Experience in Immunology and cell therapy is desired.
• Experience working with and managing relationships with CRAs in clinical sites is a plus.

Responsibilities

• Process clinical specimens, including but not limited to PBMC isolations, cell preparation and labeling, and DNA/RNA extraction.
• Develop, optimize, and perform immunologic, characteristic, and quantitative bioanalytical assays such as qPCR, ELISA, and Flow cytometry.
• Support the development and execution of translational biomarkers, PK/PD, and other clinical bioanalytical assays.
• Contribute to the planning, design, execution, and troubleshooting of high-quality experimental work.
• Document experimental procedures, observations, deviations, and results accurately and in accordance with applicable SOPs and laboratory practices.
• Interpret, summarize, and communicate results to senior scientists and/or appropriate stakeholders.
• Follow established SOPs, assay procedures, and laboratory quality requirements and contribute to the development or revision of procedures as appropriate.
• Maintain complete and well-organized laboratory records and contribute to the preparation of technical reports, study summaries, presentations, and other scientific documentation.
• Support the preparation and review of bioanalytical and translational medicine content for IND applications, regulatory submissions, and other regulatory documents, as appropriate.
• Collaborate with external laboratories, CROs, and other partners to support clinical sample testing and data delivery, as needed.
• Perform routine instrument maintenance, laboratory organization, reagent, and supply inventory management.
• Perform other duties as assigned.

Benefits

• 100% company paid medical, dental, vision, life Insurance, short-term and long-term disability insurance, and more!
• Competitive company 401k match.
• Paid holidays, sick leave, and annual leave.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Associate degree