Scientific Director

Bristol Myers Squibb • San Diego, CA

1d • $231,630 - $280,675 • Onsite

About The Position

Bristol Myers Squibb is seeking an experienced medicinal chemist to lead and contribute to drug discovery in the Protein Homeostasis Thematic Research Center within its San Diego Discovery Chemistry group. The role is part of Global Discovery Chemistry, Therapeutic Discovery Sciences, and focuses on rational design of agents with potential applications across diverse oncology indications. The successful candidate will apply modern drug design principles to medicinal chemistry challenges in collaboration with multidisciplinary scientists.

The Scientific Director leads medicinal chemistry programs from discovery through IND, contributes to scientific and portfolio strategy, and advances compounds using structural biology, ADME, and computational insights. As a member of the San Diego Chemistry Leadership team, the role also helps direct the scientific, strategic, and operational activities of the medicinal chemistry organization, including prioritization, resource allocation, talent development, and senior leadership representation.

Requirements

• Ph.D. in synthetic organic chemistry and 8 or more years of pharmaceutical medicinal chemistry industry experience; or M.S. and 12 or more years; or B.S. and 15 or more years.
• At least 6 years of program leadership experience across drug discovery phases, from program initiation to development candidate identification.
• Excellent communication skills, including presenting strategy, key data, issues, and accomplishments to members of the organization.

Nice To Haves

• Experience in protein degradation or induced proximity.
• Ph.D. in synthetic organic chemistry with 12 or more years of pharmaceutical medicinal chemistry industry experience.
• Chemistry group leadership of 5 or more team members as direct and indirect reports.

Responsibilities

• Lead end-to-end medicinal chemistry programs from discovery through IND, driving strategy, execution, and delivery of oncology assets.
• Design and advance novel compounds using modern drug design approaches, integrating structural biology, ADME, and computational insights.
• Partner with multidisciplinary teams to accelerate decision-making, shape portfolio strategy, and deliver therapeutics.
• Build, mentor, and lead scientific teams, fostering innovation, accountability, and scientific excellence within and beyond direct reporting lines.
• Present program strategy, data, opportunities, and risks to senior leadership and key stakeholders.
• As a member of the San Diego Chemistry Leadership team, guide scientific, strategic, and operational direction, including portfolio prioritization, resource allocation, talent development, and representation in senior leadership decision-making.

Benefits

• Comprehensive benefits, including wellbeing support, retirement and financial protection benefits, and medical, dental, vision, life, and disability insurance offerings.
• Eligible U.S.-based exempt employees receive Flexible Time Off without a set accrual limit, subject to manager approval, and 11 paid company holidays.
• Eligible non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires, subject to manager approval, 11 paid company holidays, and 3 optional holidays.
• Depending on eligibility, additional time-off benefits may include paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs.
• Eligible employees receive an annual Global Shutdown between Christmas Day and New Year's Day.
• Additional discretionary incentive cash and stock opportunities may be available.

What This Job Offers

• Job Type: Full-time
• Career Level: Director