(Contract) Research Technician, Pre-clinical Pharmacology

Manifold Bio•Boston, MA
•$30 - $35•Onsite

About The Position

Manifold Bio is seeking an organized, motivated In-Vivo Research Technician to join its pharmacology team on a one-year contract. The technician will work alongside experienced researchers to prepare for and execute mouse studies supporting internal drug discovery programs. The role is structured around training and growth; dosing routes, blood collection, necropsy, and tissue processing can be taught. For the right person, the contract is intended as a path toward a permanent Research Associate position. Manifold Bio is a platform biotechnology company using AI-guided protein design and massively multiplexed in vivo screening to develop tissue-targeted medicines and organism-scale models of living systems. Its team of protein engineers, biologists, and computational scientists works across the platform to pursue programs internally and with leading pharmaceutical companies.

Requirements

  • Hands-on experience with animal handling, including the ability to confidently scruff a mouse.
  • Comfort working with laboratory animals in a vivarium environment.
  • Strong organizational skills and attention to detail.
  • Ability to follow written protocols and SOPs accurately.
  • A proactive approach, including planning ahead rather than reacting.
  • Genuine enthusiasm for learning new techniques and a collaborative, team-first attitude.

Nice To Haves

  • Experience with SC, IV, or PO dosing.
  • Experience with submental blood collection.
  • Experience with necropsy and tissue dissection.
  • Experience with tissue lysis, nucleic acid extraction, or other basic bench techniques.
  • Familiarity with Benchling or similar electronic lab notebooks.

Responsibilities

  • Prepare and label tubes, cages, and collection supplies ahead of each study.
  • Set up procedure rooms for dosing days and takedowns.
  • Tattoo and tail-mark mice, and prepare and organize study cages.
  • Weigh animals and accurately record data.
  • Maintain study records in Benchling.
  • Help maintain laboratory and vivarium inventories.
  • Support necropsy and tissue collection; training is provided.
  • Process collected samples, primarily serum.
  • As time allows, assist with tissue weighing and lysis for downstream analysis.
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