Research Technician I

Mass General Brigham•Boston, MA

19h•Onsite

About The Position

The Stanton Laboratory in the Center for Genomic Medicine (CGM) at Massachusetts General Hospital (MGH) is seeking a motivated, enthusiastic candidate to join our research group. Our research group is developing technologies that can enable drug and gene delivery to the brain. The BBB has prevented multiple drugs—and especially gene therapies— from reaching the brain. A significant number of neurological diseases and psychiatric disorders have genetic causes, which could be corrected using modern gene editing technologies. However, these therapies can only be effective once they are delivered to the impacted cells in the brain, which has continued to prove to be a challenge. The candidate who will join this project will join a team working on a delivery system that can deliver genetic therapies to the brain, which could allow the treatment of many currently untreatable diseases of the brain. In this project you would perform work in: • Molecular biology techniques. • Nanoparticle formulation and characterization. • In vitro and in vivo assays for gene delivery.

Requirements

Bachelor's Degree in a related field of study required.
Prior laboratory experience, either through academic coursework, internships, or employment.
Strong theoretical and practical knowledge of laboratory techniques and procedures.
Familiarity with common laboratory equipment and instruments used in research experiments.
Proficiency in data collection, analysis, and scientific software tools.
Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively.
Strong problem-solving skills and the ability to troubleshoot technical issues.
Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges.

Nice To Haves

Prior research experience is preferred in biological assays (ELISA, flow cytometry, etc.), molecular biology (e.g., reactions such as PCR reactions, sequencing, gel assays, etc.), nanoparticle formulation and screening, nucleic acid delivery, in vitro/in vivo experiments, and/or data analysis.

Responsibilities

Perform laboratory experiments following established protocols and procedures.
Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines.
Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed.
Record experimental data accurately and maintain organized records of procedures, protocols, and results.
Compile and analyze data using appropriate statistical and analytical methods.
Assist in data interpretation and presentation, contributing to research findings and reports.