Research Specialist B
About The Position
A Research Specialist B is needed to help design, conduct and analyze experiments investigating the physiology of nuclear hormone receptors in mouse models. The Research Specialist will be working closely with the Principal Investigator and other lab members on publication-generating projects. The Research Specialist will be expected to develop novel solutions to research questions in addition to employing established methods. Prior experience with the following techniques is required: DNA/RNA extraction, molecular cloning, PCR, Q-PCR, genotyping, Western blotting, cell culture. Experience with the following techniques is highly desired: Rodent liver and/or brain survival surgery, ChIP, CRISPR screening, RNAScope, AAV purification, Next-Gen Sequencing. The position requires the daily handling of mice, including genotyping, as well as careful tracking and record keeping of mouse colonies. Good verbal and written communication skills and ability to work with other people as a team are required. Excellent organizational and record keeping skills are necessary.
Requirements
- Bachelor of Science and 2 to 3 years of experience or equivalent combination of education and experience is required.
- Prior experience in the following techniques is required: DNA/RNA extraction, molecular cloning, PCR, Q-PCR, genotyping, Western blotting, cell culture.
- Can work independently, strong communication skills (verbal and written) Strong multitasking abilities and an extremely high-level of reliability and dependability. Excellent organizational record keeping skills are required.
Nice To Haves
- Rodent liver and/or brain survival surgery
- ChIP
- CRISPR screening
- RNAScope
- AAV purification
- Next-Gen Sequencing
Responsibilities
- Help design, troubleshoot, and carry out experiments (e.g., PCR, cloning, ChIP, CRISPR screening, RNAScope, AAV purification, NGS).
- Perform complex mouse liver and brain survival surgeries.
- Perform mouse husbandry, including genotyping, and keep detailed records of mouse colonies.
- Keep a detailed lab notebook.
- Data analysis and oral and written presentation of results. Generate figures and participate in writing sections of manuscripts.
- Stay up to date on relevant literature.
- Train and supervise incoming lab members and students.
- Participate in lab management including maintenance of reagents and supplies, receiving supplies and overseeing equipment.
- Other duties and responsibilities as assigned.
Benefits
- Comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits
- Flexible spending accounts for health care and dependent care expenses
- Tuition assistance for employee, spouse, and dependent children
- Generous retirement plans (Basic, Matching, and Supplemental)
- Substantial amount of time away from work
- Long-term care insurance
- Wellness programs and resources
- Professional and personal development resources
- Access to a wide range of University resources, cultural and recreational activities
- Discounts on arts and entertainment, transportation, and mortgages
- Flexible work hours
- Forgivable loan for eligible employees interested in buying a home or currently residing in West Philadelphia
- Adoption assistance
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
