Research Specialist A

Perelman School of Medicine at the University of Pennsylvania
$45,278 - $51,000Onsite

About The Position

We are seeking a highly motivated and skilled Research Technician to join our laboratory at the Center for Neurodegenerative Disease Research (CNDR). The successful candidate will contribute to cutting-edge research investigating the role of TDP-43 protein aggregation in glial cells and its involvement in Frontotemporal Lobar Degeneration (FTLD-TDP), Amyotrophic Lateral Sclerosis (ALS), and related neurodegenerative disorders. This is an exciting opportunity to work in a collaborative research environment and gain experience with advanced cellular and molecular approaches used to study disease mechanisms.

Requirements

  • Bachelor's degree (B.A./B.S.) in Biology, Neuroscience, or a related field and 0-1 year of experience or an equivalent combination of education and experience required.
  • Previous research experience, preferably in a neuroscience, neurobiology, or cell biology laboratory.
  • Experience with cell culture techniques is highly desirable.
  • Experience with standard molecular biology, histology, and microscopy techniques is highly desirable.
  • Strong organizational, time management, and record-keeping skills.
  • Ability to work effectively both independently and as part of a multidisciplinary research team.
  • Excellent written and verbal communication skills.
  • Demonstrated commitment to scientific excellence, research integrity, and reproducible research practices.
  • Ability to prioritize multiple projects and maintain attention to detail in a fast-paced research environment.

Responsibilities

  • Conduct research on neurodegenerative diseases using primary rodent and iPSC-derived cellular models, applying a range of cell biology, molecular biology, and imaging techniques.
  • Design and perform experiments.
  • Analyze and interpret data.
  • Maintain cell cultures and accurate research records.
  • Contribute to publications, presentations, and collaborative scientific activities within the laboratory at the Center of Neurodegenerative Disease Research (CNDR).
  • Independently perform experiments using primary rat and mouse oligodendrocyte cultures, as well as induced pluripotent stem cell (iPSC)-derived neuronal and glial models.
  • Conduct a variety of in vitro assays, such as transfection, transduction, biochemical analyses, and immunocytochemistry.
  • Perform cell culture-related activities, including the establishment of non-neuronal cell lines, cryopreservation, thawing, and routine cell propagation, as needed.
  • Analyze experimental data and contribute to data interpretation.
  • Collaborate with research team members to design and execute experiments.
  • Maintain accurate and detailed records of experimental procedures and results.
  • Assist in the preparation of research reports.
  • Contribute to scientific manuscripts and presentations as appropriate.
  • Participate in laboratory meetings, scientific discussions, and Center activities.
  • Attend and present research findings at laboratory meetings and other Center-related events.

Benefits

  • Excellent healthcare benefits for employees and their families
  • Tuition benefits for employees and their families
  • Generous retirement benefits
  • Wide variety of professional development opportunities
  • Supportive work and family benefits
  • Wealth of health and wellness programs and resources
  • Comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits
  • Flexible spending accounts for health care and dependent care expenses
  • Tuition assistance for employees, spouses, and dependent children at Penn and potentially other institutions
  • Generous retirement plans (Basic, Matching, and Supplemental) with pre-tax or Roth options and investment choices through TIAA and Vanguard
  • Substantial time away from work (vacations, personal affairs, illness, family time)
  • Long-Term Care Insurance through Genworth Financial
  • Wellness and Work-life Resources
  • Professional and Personal Development resources
  • Access to a wide range of University resources, cultural and recreational activities (libraries, athletic facilities, arboretum, art galleries)
  • Discounts and special services (arts and entertainment, transportation, mortgages, new cars, cellular phone service, movie tickets, theme parks)
  • Flexible work options (non-traditional work hours, locations, and/or job structures)
  • Penn Home Ownership Services (forgivable loan for eligible employees in West Philadelphia)
  • Adoption Assistance (reimbursement for qualified expenses up to two adoptions)
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