Research Services Entry Professional

University of Colorado•Aurora, CO

8d•$47,811 - $58,861•Onsite

About The Position

The Mathew Lab investigates how systemic cytokine signaling and host inflammation shape CD8 T-cell differentiation, antitumor immunity, and responses to cancer immunotherapy. By integrating human clinical studies with mechanistic mouse models, the lab uses high-dimensional flow cytometry, single-cell transcriptomics, multiplex proteomics, and in vivo CRISPR screening to identify cytokine programs that promote durable immune priming or drive terminal T-cell dysfunction. The Department of Immunology and Microbiology at the University of Colorado Anschutz Medical Campus offers a highly collaborative environment for studying fundamental and translational immunology. Team members benefit from close connections among basic scientists, clinicians, and the broader cancer-research community, as well as access to advanced technologies, shared research resources, seminars, and professional-development opportunities. The Mathew Lab combines ambitious, rigorous science with a supportive and enjoyable team culture. Lab members are expected to be dependable, work thoughtfully, and take ownership of their projects, while receiving mentorship and opportunities to develop new experimental and analytical skills. We value curiosity, open communication, collaboration, and camaraderie—and believe that excellent science and having fun as a team should reinforce one another.

Requirements

Bachelor’s degree in biology, molecular biology, chemistry, genetics or related field
A combination of education and related technical/military/paraprofessional experience may be substituted for a bachelor’s degree on a year for year basis.
Applicants must meet minimum qualifications at the time of hire.
Applicants must be legally authorized to work in the United States without requiring sponsorship. We are unable to provide work visa sponsorship or employment authorization for this position now or in the future.
Knowledge of basic laboratory techniques including safety procedures and techniques
Ability to communicate effectively, both in writing and orally
Ability to establish and maintain effective working relationships with employees at all levels throughout the institution
Outstanding customer service skills
Demonstrated commitment and leadership ability to advance diversity and inclusion
Knowledge of basic human anatomy, physiology medical terminology
Ability to interpret and master complex research protocol information

Nice To Haves

Master’s degree in biology, molecular biology, chemistry, genetics or related field
Prior experience or background within an experimental or wet lab

Responsibilities

Collect, receive, process, and cryopreserve time-sensitive blood and tissue samples from patients participating in clinical studies.
Isolate and culture primary immune cells and prepare samples for downstream functional and molecular assays.
Perform high-dimensional flow-cytometry experiments, including antibody-panel preparation, staining, acquisition, quality control, and analysis.
Support single-cell transcriptomic, multiplex-proteomic, and CRISPR-screening workflows.
Assist with mouse models of cancer immunotherapy, including treatment administration, monitoring, tissue collection, and immune profiling.
Maintain accurate experimental records, clinical-sample inventories, databases, protocols, reagents, and laboratory equipment while following institutional safety and regulatory requirements.