Medicinal Organic Chemist - Chemical Biology (BS or MS)

NovartisCambridge, MA
$66,800 - $150,800Onsite

About The Position

The Discovery Sciences team is seeking a Research Scientist to work as an organic medicinal chemist at Novartis’ Biomedical Research headquarters in Cambridge, MA, USA. In this lab-based role, with team assistance, you will carry out multi-step organic chemistry synthesis routes preparing organic molecules that test molecular biology hypotheses and interrogate molecular pathways implicated in disease. You will leverage your expertise in mechanistic organic chemistry to effect functional group transformations building up complex structures. You will use modern purification techniques for final product isolation and then gather and analyze characterization data for structural confirmation. You will analyze assay results using data tools and leveraging Data Science and A.I. to work through the Design, Make, Test, Analyze (DMTA) cycle.

Requirements

  • BS or MS degree in chemistry; 0-5 years of industrial experience. This is not a PhD-level position.
  • A mechanistic understanding of organic chemistry; knowledge of modern organic synthetic methods; medicinal chemistry knowledge is a plus
  • Familiarity with common chemistry synthesis, purification, and analytical techniques
  • Strong problem solving and communication skills

Nice To Haves

  • Expertise in chemical biology and synthesis of chemical probes to address impactful biological and conceptual questions.
  • Hands-on experience in synthesis of a wide range of compound classes, practical techniques, method development, and purification techniques.

Responsibilities

  • Design compounds based off team or individual hypotheses, and carry out multi-step syntheses of small molecules
  • Analyze and interpret data, solve synthetic issues and design follow-up experiments
  • Collaborate with peers and work effectively and efficiently as an important part of a cross-functional team
  • Adhere to laboratory safety policies and practices

Benefits

  • performance-based cash incentive
  • eligibility to be considered for annual equity awards
  • health, life and disability benefits
  • a 401(k) with company contribution and match
  • a variety of other benefits
  • generous time off package including vacation, personal days, holidays and other leaves
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