Research Lab Tech I NEUROLOGY rl

Mass General Brigham•Boston, MA

1d•Onsite

About The Position

The Ann Romney Center for Neurologic Diseases seeks a motivated Research Lab Tech I to investigate the role of the microbiome and immune system in models of neurologic disease. Under the general supervision of Rafael Rezende, the Research Lab Tech performs routine and non-routine experiments, including administering treatments to animal models, characterizing behavior and pathology, and conducting laboratory procedures such as flow cytometry, ELISAs, DNA extraction, PCR, and bacterial culture. The role includes recording results, maintaining accurate laboratory notes, and managing laboratory supplies. Training will be provided for specific procedures. Candidates are asked to submit a cover letter describing their research experience, ability to work collaboratively, and motivation for applying. Candidates should be able to commit to the position for two years.

Requirements

Bachelor's degree in a related field, or qualifying experience in lieu of a degree.
Prior laboratory experience through academic coursework, internships, or employment; 1–2 years preferred.
Sound understanding of laboratory practices and procedures, typically acquired through one to three months of on-the-job training.
Ability to follow instructions, manage work neatly and orderly, and work independently and collaboratively.
Ability to multitask and prioritize work with attention to detail and punctuality.
Ability to identify potential problems and troubleshoot independently.
Good manual dexterity and ability to carry items weighing up to 30 lbs.
Good organizational, record-keeping, interpersonal, oral, and written communication skills; attention to detail and professionalism.
Computer literacy and strong theoretical and practical knowledge of laboratory techniques and procedures.
Familiarity with common laboratory research equipment and instruments.
Proficiency in data collection, analysis, and scientific software tools.
Strong problem-solving skills and ability to troubleshoot technical issues.
Ability to commit to the position for two years.

Nice To Haves

Experience with laboratory procedures.
Experience working with mice.

Responsibilities

Administer bacteria or immunomodulatory agents to animal models of neurologic disease, including handling mice, giving intraperitoneal, subcutaneous, and intravenous injections, and conducting behavioral tests.
Learn to operate flow cytometry equipment.
Perform immunology techniques, including ELISA and western blot, and basic procedures on laboratory animals.
Perform molecular biology techniques, including RNA and DNA purification and cloning.
Maintain mouse colonies and records of mouse strains and breeding.
Culture and maintain cell lines and hybridomas.
Culture bacteria from the microbiome and maintain stocks.
Perform molecular experiments, including DNA extraction and 16S rRNA amplicon library preparation.
Maintain and order supplies and help keep the laboratory area clean and orderly.
Maintain a laboratory notebook documenting daily activities, experiments, and procedures.
Search and review literature, compile information, suggest research techniques, and exchange information with other researchers and technicians.
Attend safety training and ensure laboratory activities comply with procedures for handling, storing, and disposing of biohazardous, infectious, radioactive, and toxic substances.
Perform laboratory experiments according to established protocols and procedures.
Prepare and handle samples, reagents, and solutions accurately and in accordance with safety guidelines.
Operate and maintain laboratory equipment and instruments, including routine calibration and troubleshooting.
Accurately record experimental data and maintain organized records of procedures, protocols, and results.
Compile and analyze data using appropriate statistical and analytical methods.
Assist with data interpretation and presentation and contribute to research findings and reports.
Perform other duties as assigned or as the position requires.