Research Lab Tech I NEUROLOGY rl

Mass General Brigham•Boston, MA

1d•$21 - $29•Onsite

About The Position

The Ann Romney Center for Neurologic Diseases is seeking a motivated Research Lab Tech I to investigate the role of the microbiome and immune system in models of neurologic disease. Working under the general supervision of Rafael Rezende, the Research Lab Tech performs routine and non-routine experiments, including administering treatments to animal models, characterizing animal behavior and pathology, performing flow cytometry, ELISAs, DNA extraction, PCR, and bacterial culture. The role also involves documenting results and maintaining accurate laboratory notes and supplies. The position requires laboratory experience and work with mice; training will be provided for specific procedures. Applicants should submit a cover letter describing their research experience, ability to work collaboratively, and motivation for applying. The employer seeks candidates able to commit to the position for two years. Candidates completing a bachelor's degree may have six months from their hire date to provide degree-equivalency verification, or up to one year if starting per diem.

Requirements

Bachelor's degree in a related field, or qualifying experience in lieu of a degree.
Prior laboratory experience through academic coursework, internships, or employment; 1–2 years preferred.
Ability to manage work neatly and orderly, follow instructions, and work independently and collaboratively.
Ability to multitask and prioritize work with attention to detail and punctuality.
Ability to identify potential problems and troubleshoot on one's own initiative.
Good manual dexterity and ability to carry items weighing up to 30 pounds.
Good organizational and record-keeping skills and attention to detail.
Good interpersonal, oral, and written communication skills; professionalism.
Computer literacy.
Sound understanding of laboratory practices and procedures, typically acquired through one to three months of on-the-job training.
Strong theoretical and practical knowledge of laboratory techniques and procedures.
Familiarity with common research laboratory equipment and instruments.
Proficiency in data collection, analysis, and scientific software tools.
Strong problem-solving skills and ability to troubleshoot technical issues.
Ability to commit to the position for two years.

Nice To Haves

Experience working with mice.
Experience with laboratory procedures.

Responsibilities

Administer bacteria or immunomodulatory agents to animal models of neurologic disease, including handling mice, giving intraperitoneal, subcutaneous, and intravenous injections, and conducting behavioral tests.
Learn to operate flow cytometry equipment.
Perform immunology techniques, including ELISA and western blot, and basic procedures on laboratory animals.
Perform molecular biology techniques, including RNA and DNA purification and cloning.
Maintain mouse colonies and records of mouse strains and breeding.
Culture and maintain cell lines and hybridomas.
Culture bacteria from the microbiome and maintain bacterial stocks.
Perform routine molecular experiments, including DNA extraction and 16S rRNA amplicon library preparation.
Maintain and order supplies and help keep the laboratory clean and orderly.
Maintain a laboratory notebook documenting daily activities, experiments, and procedures.
Conduct literature searches and reviews, compile journal information, suggest research methods, and exchange information with researchers and technicians.
Attend safety training and ensure laboratory activities comply with procedures for handling, storing, and disposing of biohazardous, infectious, radioactive, and toxic substances.
Perform experiments according to established protocols and procedures.
Prepare and handle samples, reagents, and solutions accurately and safely.
Operate and maintain laboratory equipment, perform routine calibration, and troubleshoot as needed.
Accurately record experimental data and maintain organized records of procedures, protocols, and results.
Compile and analyze data using appropriate statistical and analytical methods.
Assist with data interpretation and presentation and contribute to research findings and reports.
Perform other duties as assigned or required.