Research Fellow - Hematology - Mondello lab
About The Position
The Mondello lab is seeking a post-doctoral research fellow with 2-3 years of prior wet lab experience in a relevant biomedical field such as molecular biology, immunology, and/or genomics. The lab's research focuses on epigenetic dysregulations in B cell malignancy and their impact on the tumor microenvironment. Utilizing genomic, epigenomic, and transcriptomic profiling of patient samples and lymphoma cell lines, alongside genetically modified mouse models, the lab aims to identify and functionally characterize genetic lesions affecting chromatin modifiers and transcription factors. The research will determine the role of these alterations in modulating tumor-immune crosstalk and ultimately inform the development of therapeutic strategies. The fellow will be expected to perform bench work including viral transfection, immunoprecipitation, flow cytometry, western blotting, and mouse work such as immunization, transplant, genotyping, and colony maintenance. While prior experience in these techniques is expected, additional training will be provided. This position requires the applicant to work on site.
Requirements
- Ph.D., M.D., or equivalent doctoral degree in a relevant field.
- 2-3 years of wet lab experience in a relevant biomedical field (e.g., molecular biology, immunology, and/or genomics).
- Prior experience in techniques such as viral transfection, immunoprecipitation, flow cytometry, western blotting, mouse immunization, transplant, and genotyping is expected.
- Must have completed no more than one prior postdoctoral fellowship, at Mayo Clinic or elsewhere.
Responsibilities
- Execute bench work, including viral transfection, immunoprecipitation, flow cytometry, and western blotting of primary and lymphoma cell lines.
- Perform mouse work, including immunization, transplant, genotyping, and mouse colony maintenance.
- Identify and functionally characterize recurrent genetic lesions affecting chromatin modifiers and transcription factors.
- Determine the role of these alterations in modulating tumor-immune crosstalk.
- Contribute to the development of specific and potent therapeutic strategies.
Benefits
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
- Continuing education and advancement opportunities.
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
Ph.D. or professional degree
