Research Associate - Jiang Lab

UVA HealthCharlottesville, VA
Onsite

About The Position

The Lulu Jiang Lab at the University of Virginia (UVA) is seeking a talented individual to join our dynamic research team as a Postdoctoral Research Associate. The Lulu Jiang Lab is dedicated to advancing our understanding of the intricate workings of the brain, with a strong emphasis on comprehending the pathophysiology of neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD), and other related dementia disorders. Our primary objective is to deepen our understanding of these disease conditions. To achieve this, we employ cutting-edge technologies in disease modeling, allowing us to recreate and study the pathological processes in a controlled environment. By utilizing these advanced techniques, we gain insights into the intricate molecular mechanisms that underlie the progression of these diseases. Moreover, our lab is dedicated to the development of innovative therapeutic strategies. We strive to translate our research findings into practical applications that could potentially lead to the discovery of novel treatments. By integrating our knowledge of disease mechanisms with targeted therapeutic approaches, we aim to make significant contributions to the field of neurodegenerative disease research. Overall, our lab is committed to advancing the understanding, diagnosis, and treatment of neurodegenerative diseases through the utilization of state-of-the-art technologies and the exploration of molecular mechanisms. Our research focuses on several key areas that drive our scientific interests and contribute to the understanding and treatment of neurodegenerative diseases. These areas include: Investigation of RNA modifications and epitranscriptomic mechanisms in the pathogenesis of Alzheimer's disease (AD) and related dementias. Exploration of neuron-glia interactions and neuroimmunological mechanisms underlying the progression of AD and Parkinson's disease (PD). Utilization of iPSC-induced 3D human brain organoid models to study neurodegenerative diseases and enable precision medicine approaches. Elucidation of the molecular mechanisms driving prion-like propagation in the Braak stages of AD. Development of innovative genetic and small molecule therapeutics for neurodegenerative diseases. These research directions represent our current focus and ongoing projects, which collectively contribute to the advancement of knowledge and the development of new strategies for the management and treatment of neurodegenerative diseases. With state-of-the-art facilities and a collaborative environment, we strive to foster creativity, innovation, and scientific excellence.

Requirements

  • Doctoral degree

Responsibilities

  • Conducting experiments and data analysis related to ongoing research projects.
  • Contributing to the development and implementation of research protocols.
  • Collaborating with fellow researchers and scientists within and outside the lab.
  • Presenting research findings at conferences and publishing in scientific journals.
  • Assisting in the training and mentorship of junior lab members.

Benefits

  • Exempt-level, benefited position
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