The Yang lab is seeking a research associate to join their lab within the Biochemistry and Molecular Genetics Department at the University of Virginia. The duties of this position include general lab maintenance and direct participation in cutting edge research experiments. The Yang Lab is dedicated to dissecting the molecular mechanisms of cellular stress response, specifically focusing on mitochondrial stress, endoplasmic reticulum (ER) stress, and downstream integrated stress response (ISR). We employ an interdisciplinary approach, integrating structural biology (Cryo-EM/Cryo-ET), biochemistry (protein characterization), and cell biology (fluorescent imaging). Our ultimate goal is to modulate those stress response pathways in physiological and pathological conditions, potentially leading to the development of novel therapeutics for related human diseases, including neurodegeneration, metabolic disorders, and cancer. In addition, we have established close collaborations with experts in disease-relevant mouse models to complement our mechanistic findings. We welcome applications from individuals interested in investigating the fundamental aspects of any significant biological processes.
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Job Type
Full-time
Career Level
Executive
Education Level
Ph.D. or professional degree