Research Associate II, Biochemistry & Molecular Biology (Galveston)

University of Texas Medical Branch (UTMB)•Galveston, TX

About The Position

The Center for Genome Architecture studies how the genome folds inside the nucleus and how that organization affects biological processes. The Center has produced high-resolution three-dimensional maps of the human genome, identified chromatin loops and contact domains as key features of genome organization, and investigated how loop extrusion and cohesin contribute to these structures. The Center is expanding its experimental work, including a growing mouse research program, to study these principles in living tissues and explore the use of these technologies as a diagnostic. The Research Associate II performs molecular biology work and sequencing library preparation, contributes to analysis and quality control of resulting data, and troubleshoots and optimizes protocols. The role also participates in mouse work, including colony management, genotyping, treatment, and tissue collection. Prior mouse experience is a plus but is not required. Under general supervision, the position performs routine and non-routine research assignments and experiments of moderate complexity and assists with laboratory maintenance.

Requirements

  • Bachelor's degree in basic science or equivalent and 2 years of related experience, or a master's degree in basic science or equivalent with no experience required.
  • Experience or skills in biological assays, quantitative analysis, qualitative analysis, data analysis, tabulation of data, equipment calibration, technical writing, and standard laboratory equipment.

Nice To Haves

  • Prior mouse experience.

Responsibilities

  • Perform routine and non-routine research assignments and experiments of moderate complexity.
  • Plan, coordinate, set up, and conduct standard research experiments following general technical instructions.
  • Perform molecular biology work and sequencing library preparation.
  • Prepare biological assays and conduct quantitative and qualitative analyses.
  • Troubleshoot and optimize protocols, and modify research procedures as determined by the Principal Investigator.
  • Contribute to analysis and quality control of resulting data.
  • Maintain records of tests performed and data collected, and provide preliminary analysis of results.
  • Assist with compiling and tabulating data and analyzing final data.
  • Ensure accurate assembly, calibration, operation, and modification of laboratory equipment in accordance with applicable guidelines.
  • Participate in mouse work, including colony management, genotyping, treatment, and tissue collection.
  • Maintain the laboratory in compliance with animal and environmental safety requirements.
  • Maintain laboratory inventory of supplies and equipment.
  • Perform literature searches as outlined by the Principal Investigator.
  • May provide guidance to junior research staff.
  • Adhere to internal controls established for the department.
  • Perform related duties as required.
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