Research Associate, Molecular & Cellular Immunology

Stylus Medicine • Cambridge, MA

23d

About The Position

Stylus Medicine is developing in vivo genetic medicines using engineered recombinases and non-viral delivery. The Research Associate will join the Molecular and Cellular Immunology team and assist in generating nucleic acid materials and conducting in vitro cell experiments to support genetic medicines that use engineered recombinases delivered through non-viral methods. The role involves working closely with cross-functional teams and contributing to the development of transformational therapies.

Requirements

• Bachelor’s degree in Biology, Bioengineering, Immunology, or a related field.
• Hands-on molecular biology experience, including PCR, cloning, bacterial transformations, minipreps, maxipreps, and in vitro transcription.
• Hands-on mammalian cell culture expertise, including culturing tumor cell lines and primary T cells/PBMCs, co-culture experiments, flow cytometry, and genomic DNA extraction.
• Ability to execute, interpret, and troubleshoot experiments independently and collaboratively.
• Experience maintaining meticulous records, including an organized lab notebook, lab inventory, and experimental results.
• Excellent communication skills, a team-first mindset, and ability to convey technical information.
• Highly collaborative working style and ability to adapt in a fast-paced, rapidly developing environment.
• Enthusiasm and curiosity to learn and apply new laboratory techniques across a variety of sub-disciplines.

Nice To Haves

• Familiarity producing targeted LNPs and/or working with CAR-T cells.

Responsibilities

• Perform in vitro T cell experiments to evaluate the efficiency of recombinase-based engineering strategies and characterize the function of resulting CAR-T cells.
• Perform cloning and prepare nucleic acid materials and/or LNPs to support cell culture experiments.
• Analyze and interpret data and produce reports to inform project direction.
• Communicate findings effectively to internal teams.
• Maintain detailed and accurate laboratory records in compliance with data integrity and documentation standards.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level