Research Associate, Platform Technology

Deep Genomics•Cambridge, MA

2d•$75,000 - $90,000

About The Position

Deep Genomics is seeking a passionate and detail-oriented Research Associate to join their Platform Technology team. This role involves contributing hands-on to an AI-driven drug discovery platform by generating experimental data that informs biological models for therapeutic development. The position offers exposure to cutting-edge technologies such as NGS workflows, liquid handling automation, and various RNA therapeutic modalities. It is an opportunity for early-career professionals to gain experience in a cross-functional discovery environment and contribute to impactful therapeutic work.

Requirements

BS in Molecular Biology, Genetics, Genomics, Biotechnology, Biochemistry, or a related discipline with 1–3 years of relevant industry or research experience (including internships or postgraduate research).
Foundational knowledge of molecular and cell biology principles.
Some hands-on exposure to amplicon sequencing or other targeted NGS workflows; broader NGS experience is also welcomed.
Experience with nucleic acid extraction, quantitation, and standard molecular biology techniques such as PCR, qPCR or d(d)PCR, gel electrophoresis.
Strong attention to detail and commitment to rigorous, reproducible lab work.
Ability to work both independently and collaboratively in a team-oriented environment.

Nice To Haves

Proficiency with liquid handling platforms such as Hamilton, Beckman, or Bravo.
Working familiarity with RNA therapeutic modalities such as ADAR editing, ASOs, siRNAs, or mRNA.
Experience with mammalian cell culture, including transfection-based assays.
Prior exposure to a biotechnology, pharmaceutical, or platform-driven research environment.

Responsibilities

Execute amplicon sequencing workflows, including NGS library preparation and targeted sequencing, under the guidance of senior team members, to support the evaluation of RNA therapeutic candidates.
Carry out library QC using tools such as TapeStation, Qubit and qPCR, flagging workflow bottlenecks to ensure high-quality datasets for downstream computational analysis.
Operate sequencing instruments such as the Illumina NextSeq, including run setup and routine troubleshooting, with increasing independence over time.
Perform routine molecular biology techniques including PCR, qPCR/ddPCR, and nucleic acid extractions from a variety of cell types and tissues.
Assist in running automated workflows on liquid handling platforms (e.g., Hamilton STAR, Agilent Bravo, Beckman Echo) to support scaling of discovery and screening activities.
Maintain accurate and thorough documentation of experimental plans, results, SOPs, and troubleshooting steps within an electronic lab notebook (ELN).
Contribute to team meetings and share experimental results and assay updates with immediate project collaborators.