Research Associate - RNA Synthesis Platform Development

Sanofi•Waltham, MA

13d•Hybrid

About The Position

Are you passionate about advancing RNA therapeutics and cutting-edge biotechnology? We're seeking a talented Research Associate - RNA Synthesis Platform Development to join our dynamic team in Waltham, where innovation meets impact in the rapidly evolving world of mRNA technology. Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions. About Sanofi: We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Requirements

Bachelor's degree in Biochemistry or related fields.
Minimum 2 years of hands-on experience in an industrial laboratory setting.
Strong background in enzymatic reactions and catalysis, with particular emphasis on in vitro transcription (IVT) reactions and enzyme kinetics.
Demonstrated expertise in RNA synthesis, protein and nucleic acid biochemistry, and enzymatic process development (preferably in mRNA manufacturing).
Experience with Hamilton Vantage automated systems and Venus software for liquid handling methods.
Proficiency in RNA purification and characterization assays including Ethanol precipitation, Spectrophotometry, Capillary electrophoresis, ELISA and qPCR methodologies.
Strong experimental design skills and quantitative data analysis capabilities.
Fluency in English (written and verbal).
Detail-oriented with excellent organizational skills.
Collaborative mindset with strong communication abilities.
Adaptability in a fast-paced, innovative environment.

Responsibilities

Support individual program development through the application of cutting-edge platform synthesis technologies.
Evaluate and develop new technologies for improving current platform processes, pushing the boundaries of what's possible in RNA synthesis.
Operate and optimize Hamilton Vantage automated systems and liquid handling platforms using Venus software.
Design and execute enzymatic reactions with a focus on in vitro transcription and enzyme kinetics.
Perform comprehensive nucleic acid purification and characterization using advanced analytical techniques.
Design experiments and conduct quantitative data analysis to drive scientific conclusions.