Research Associate II - T Cell Therapeutics Research Laboratory

City of Hope • Duarte, CA

2d

About The Position

The Research Associate II will work in Dr. Christine Brown’s T Cell Therapeutics Research Laboratories (TCTRL) at the Beckman Research Institute of City of Hope. The laboratory conducts research and clinical immunotherapeutic programs. The role supports evaluation of CAR T-cell therapies in next-generation cancer models, including patient-derived organoid cultures and organ-on-a-chip platforms, and the development and evaluation of blood- and iPSC-derived immune effector cell therapies. Training in project-specific techniques and procedures will be provided. Work hours may vary.

Requirements

• Bachelor’s degree.
• At least 2 years of related experience with a bachelor’s degree, or at least 1 year of related experience with a master’s degree.
• Meticulous attention to detail and accuracy in laboratory work.
• Accurate recordkeeping and laboratory documentation.

Nice To Haves

• Master’s degree preferred.
• Hands-on experience with cellular immunology and standard Good Laboratory Practices (GLP) desired.

Responsibilities

• Perform tissue culture using aseptic techniques, including media preparation, passaging, maintenance, and cryopreservation of T-cell lines and pluripotent stem cells.
• Support development of next-generation solid cancer models, including patient-derived organoids and tumor-on-a-chip platforms.
• Conduct T-cell functional assays, including cytotoxicity and cytokine production assays, as well as ELISAs.
• Perform cell staining for multicolor flow cytometry and analyze flow cytometry data.
• Assist with murine surgical procedures, tissue harvesting, and sample preparation.
• Revise and maintain laboratory protocols and procedures.
• Provide routine laboratory support and maintenance in accordance with Good Laboratory Practice (GLP) principles.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level