Research Associate, Downstream Process Development

Avid Bioservices•Tustin, CA

2d•Onsite

About The Position

Avid Bioservices is a leading clinical and commercial biologics CDMO focused on creating innovative solutions to meet the needs of our clients and improve patient outcomes. The Research Associate, Process Development Downstream will provide laboratory support for Process Development by assisting in the downstream process and/or method development. The Research Associate may be assigned various tasks within the department and outside the department as needed.

Requirements

Bachelor's degree with 1-2 years of relevant biopharmaceutical industry experience, in Chemical Engineering, Biochemical Engineering, Biotechnology, Biological Sciences, or a related field.
Strong understanding of downstream processing principles, experimental design, data analysis, and bioprocess development methodologies.
Exceptional multitasking skills and an unparalleled attention to detail.
Mastery at building relationships, capable of establishing connections with anyone, be it team members, clients, vendors, or suppliers.
Excellent written and verbal skills, communicating with clarity and confidence.

Nice To Haves

Experience with laboratory automation, process intensification, and data analytics is highly desirable.

Responsibilities

Serve as a subject matter expert (SME) and/or technical lead for downstream process development and purification of monoclonal antibodies, recombinant proteins, and related biologics. Responsibilities include buffer formulation and preparation, chromatography process development and optimization, filtration development, and routine process execution.
Lead downstream process development studies, including chromatography screening, process optimization, and scale-up activities to support client programs from early development through commercialization.
Perform and oversee in-process and routine analytical testing to support downstream development activities, including protein concentration determination (A280), HPLC-based assays, and other relevant analytical methods.
Independently execute downstream unit operations using chromatography systems, filtration equipment, and associated process analytical tools with minimal supervision.
Support process scale-up, technology transfer, and manufacturing operations by developing robust buffer preparation strategies and downstream processing workflows suitable for pilot and GMP manufacturing environments.
Compile, analyze, interpret, and present experimental data.
Author technical reports, development summaries, protocols, and client-facing documentation, and present findings during internal project reviews and client meetings.
Lead troubleshooting and continuous improvement initiatives to enhance process performance, robustness, productivity, and scalability.
Contribute to the evaluation, implementation, and validation of emerging technologies, process analytics, laboratory automation platforms, and process intensification strategies to improve development efficiency.
Perform other duties and project-related responsibilities as assigned.