Research Associate, Cell Line Development
About The Position
Prolific Machines is seeking a skilled Research Associate to join their Cell Line Development team. This role will contribute technically and scientifically to the advancement of multiple projects, bringing innovation and new perspectives to workflows. The position is based on-site in Emeryville, CA and reports to a Principal Scientist of the Cell Line Development department. This is an individual contributor role focused on hands-on execution, instrumentation, and technical operations in a laboratory setting, with growth opportunities in deepening technical expertise, expanding instrument proficiency, and taking on increasing operational responsibility.
Requirements
- A Bachelor’s degree in Biology or equivalent with 2 or more years of experience.
- Extensive hands-on experience with mammalian cell culture techniques.
- Careful and accurate working style, quality awareness.
- Proficiency in Microsoft Office Suite (Excel, Word, Outlook, and Teams).
- Data analytic software, such as GraphPad Prism.
- Experience executing batch and fed-batch culture studies as part of cell line development and upstream process development activities.
- Experience with bench-scale bioreactor set-up and operation (mammalian culture).
- Experience with basic molecular biology techniques (PCR, ligation cloning, gel electrophoresis, etc.).
Nice To Haves
- Previous experience in industry is a plus.
- Familiarity with fully-automated instrumentation (FACS, Octet, Cell Printer, etc.) for the selection of high-producing clones used in antibody discovery and cell line development.
Responsibilities
- Contribute to the maintenance of an internal cell line bank, including banking of new cell lines and ensuring the quality of cell lines for Research purposes.
- Develop and engineer new cell lines.
- Assessment and quantification of target antigen expression.
- Design and perform cell-based and protein analysis assays.
- Contribute to improvement of processes and techniques.
- Analysis and interpretation of data and presentation to internal stakeholders.
- Maintain a close collaboration with cross-functional project teams.
- Maintain accurate and timely up-to-date documentation (familiarity with ELNs).
- Update and optimize local guidelines / SOPs for the team.
- Routine maintenance of the Tissue Culture labs.
Benefits
- Generous equity package in an early stage company
- Retirement plan with company contribution
- Flexible PTO with healthy time off minimums
- Company-covered medical, dental, and vision insurance
- Life and disability insurance
- Career coaching
- Mental health support
- Free team lunches everyday
- Great snacks
- Companywide social events
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
