Research Assistant II, Rare Disease Translational Center

The Jackson Laboratory • Bar Harbor, ME

1d

About The Position

The Rare Disease Translational Center (RDTC) at The Jackson Laboratory develops clinically relevant mouse and cell-based/in vitro models with clinical mutations and uses them to study disease and test potential therapies, including gene therapy and RNA-based treatments. The Research Assistant II supports preclinical studies by characterizing disease in research models and generating high-quality data. Work spans phenotyping and molecular workflows, including tissue collection, histology, microscopy and quantitative image analysis, molecular assays, and omics approaches such as RNA-seq and proteomics. The role owns defined workstreams from start to finish and contributes to translational research decisions. The RDTC works with foundations and their basic and clinical research teams in support of The Jackson Laboratory’s mission to discover precise genomic solutions for disease and improve human health.

Requirements

• Bachelor’s degree required.
• At least 2 years of experience required.
• Comprehensive mouse handling and husbandry skills.
• Demonstrated ability to develop research protocols.
• Demonstrated success coordinating or conducting multiple concurrent assignments or a multifaceted project.
• Ability to interact productively and professionally with individuals to support research program goals.
• Established understanding of laboratory safety practices and a demonstrated history of safe laboratory conduct.
• Self-motivation and effective time and detail management.
• Advanced computer skills and ability to develop technical documents and presentations.
• Team-oriented, professional, positive attitude, and willingness to be flexible.
• Ability to work flexible shifts, including evenings, weekends, and holidays.
• Regular, reliable, and consistent attendance.

Nice To Haves

• Four years of experience preferred.
• Bachelor’s degree preferred.

Responsibilities

• Troubleshoot research procedures, adjust techniques or quality-control measures, and identify when methods need refinement.
• Review and maintain research documentation, contribute to methodology updates, and collaborate with team members as needed.
• Manage laboratory resources, including inventory, equipment, and workspace coordination.
• Demonstrate procedures, share research knowledge, and assist with training.
• Perform assigned research tasks using established experimental methods, equipment, data collection tools, and analytical techniques.
• Organize, analyze, and summarize research data using scientific and statistical tools.
• Contribute to manuscripts, reports, presentations, and grant materials.
• Conduct multiple experiments, maintain associated equipment, and communicate results clearly and promptly.
• Apply mouse handling and husbandry skills to support research operations.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level