R&D Assay Development Intern

Promega•Madison, WI

About The Position

The R&D Assay Development Intern will contribute to projects developing bioluminescent and fluorescent tools for studying processes in living cells and biochemical systems. Projects may involve NanoLuc-based reporter and complementation technologies such as NanoBiT and HiBiT; homogeneous, no-wash bioluminescent immunoassays for intracellular proteins and post-translational modifications; fluorescence labeling, imaging, and plate-reader methods; enzyme activity assays; and drug discovery applications including assay miniaturization, high-throughput screening, and compound profiling. The intern will perform cell culture, transfections, and cell-based assays in multi-well formats; run biochemical assays; use luminometers, fluorescence plate readers, and imaging instruments; and collect, organize, and analyze assay data. They will document work in an electronic lab notebook, follow protocols with direction, learn to troubleshoot unexpected results, present findings at group meetings, and contribute ideas. The role involves applying Promega proprietary technologies to develop intracellular target detection and signaling assays while working at the bench and collaborating with the team.

Requirements

Must be currently enrolled in a degree program in the life sciences, such as biology or chemistry.
Demonstrated proficiency in digital tools and technology, including Microsoft applications and mobile platforms, with the ability to adapt to and leverage emerging technologies such as artificial intelligence to improve efficiency, automation, and collaboration.

Nice To Haves

Experience with cell culture is desirable.

Responsibilities

Perform cell culture, transfections, and cell-based assays in multi-well formats.
Run biochemical assays, including reagent preparation, buffer optimization, and titrations.
Operate luminometers, fluorescence plate readers, and imaging instruments.
Collect, organize, and analyze data, including dose-response curves, signal-to-background, Z’ factor, and assay window.
Document experiments clearly in an electronic lab notebook.
Follow protocols with direction, learn to troubleshoot, and ask questions when results are unexpected.
Present results and contribute ideas at group meetings.
Apply Promega proprietary technologies to develop intracellular target detection and signaling assays.
Become competent in applying one or more techniques.
Work with cultured cells to develop detection assays.
Understand their role in the team environment and interact effectively with co-workers and team members.
Follow the project plan with assistance and work at the bench.
Demonstrate inclusion through words and actions, support a safe workspace, and act with kindness, curiosity, and respect for others.
Be open to incorporating Promega’s six Emotional & Social Intelligence (ESI) core principles in daily work.
Understand and comply with ethical, legal, and regulatory requirements applicable to the business.