QC Technician - RNA/LNP Production

GenScript ProBio•Redmond, WA

3d•Onsite

About The Position

GenScript Biotech Corporation is a global biotechnology group with a presence in North America, Europe, Greater China, and Asia Pacific. Founded in 2002, GenScript operates in life science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy. The company is committed to making humans and nature healthier through biotechnology and is a leader in life sciences research tools and services, offering solutions in gene synthesis, protein expression, antibody development, and mRNA/LNP technologies. The mRNA & LNP Services team provides end-to-end solutions for vaccine and therapeutic development, including sequence design, IVT mRNA synthesis, LNP formulation, analytics, and QC release testing. GenScript is seeking a detail-oriented and technically skilled QC Technician to join their mRNA & LNP Service Team. This role involves performing analytical testing and quality control assays to ensure the integrity, purity, potency, and consistency of mRNA products and lipid nanoparticle formulations. The QC Technician will collaborate with R&D, Manufacturing, QA, and Project Management teams to support client projects and internal process improvements.

Requirements

Bachelor's degree in molecular biology, chemistry, biochemistry, pharmaceutical science or related field.
Ability to communicate efficiently verbally and in writing.
Ability to perform in a fast-paced environment with high product throughput.
Ability to follow detailed instructions, maintain accurate records and notes, and carry out assignments in a thorough, conscientious fashion while adhering to safe laboratory practices.
A sense of humility and an eagerness to continue to learn and contribute to a supportive team.

Nice To Haves

Master's degree preferred.
Experience with HPLC, LC-MS, ELISA, cell culture, and flow cytometry is preferred.

Responsibilities

Supporting communication with the production manager and team, contributing to a working environment that encourages employee involvement and collaboration.
Conducting analytical assays including but not limited to: RNA concentration and purity (UV spectrophotometry, fluorometry), RNA integrity (Agilent Bioanalyzer, gel electrophoresis), dsRNA contamination (ELISA, immunoblot, HPLC), LNP particle size and polydispersity (DLS, others), Encapsulation efficiency (ribogreen assay, dye exclusion), Endotoxin testing, pH, osmolality, sterility (as applicable).
Reporting out-of-specification results and deviations to the manager.
Assisting with investigations, root cause analysis, and reports for out-of-specification results and deviations.
Ensuring timely completion of QC reports after production job completion.
Accountability for QC report compliance with good documentation practices.
Supporting process improvement initiatives within the scope of responsibility.
Monitoring supply inventory and identifying any products required.
Maintaining work area, equipment, department, and all storage areas in a clean, neat, and orderly manner.
Performing other duties as needed.