Process Development Engineer I, Late-Stage Purification

Regeneron Pharmaceuticals • Tarrytown, GA

2d • $80,300 - $131,100 • Onsite

About The Position

Regeneron is seeking a Process Development Engineer I to join the Late-Stage Purification Development team within Preclinical Manufacturing and Process Development (PMPD). This on-site role is based in Tarrytown, New York. The engineer will develop and transfer harvest, affinity chromatography, and viral inactivation processes for recombinant proteins using Quality by Design principles, collaborating with process development and manufacturing colleagues. The position offers the opportunity to contribute to a science-driven organization developing medicines for people with serious diseases.

Requirements

• Bachelor's or Master's degree in Chemical Engineering, Biochemical Engineering, Biochemistry, or a related field.
• 0–2 years of recombinant protein purification experience.
• Hands-on experience with techniques such as depth filtration, disc stack centrifugation, column chromatography, virus retentive filtration, ultrafiltration/diafiltration, and buffer preparation.
• Understanding of and practical experience in purifying monoclonal antibodies or other biopharmaceuticals.
• Experience with process automation, such as hardware, control logic, and/or HMI development.
• Ability to thrive in a team-based, collaborative environment, stay well-organized, and manage multiple projects efficiently.

Nice To Haves

• Strong fundamental understanding of protein purification techniques.
• Experience with Akta chromatography systems, HPLC, UPLC, Empower, Unicorn, JMP, LIMS, Python, Ignition, and PI Historian.

Responsibilities

• Design and execute experiments at bench and pilot scale.
• Analyze data, draw conclusions, and propose next steps.
• Document results in laboratory notebooks and reports, and share findings with functional area and department leadership.
• Serve as a purification development subject matter expert during manufacturing process transfer to support successful GMP batches.
• Collaborate cross-functionally with the process development team to enable a robust, cohesive manufacturing process.
• Support technology development, including automating pilot-scale unit operations, improving bench-scale process models, building historical data workflows, and evaluating new raw materials, equipment, or techniques.
• Train and mentor peers, co-op students, and interns in running experiments, analyzing data, and documenting results.
• Contribute to lab equipment maintenance and lab safety.

Benefits

• Competitive and comprehensive total rewards package, which may include annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, medical, dental, vision, life and disability insurance, paid time off, and family support benefits.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level