About The Position
Parexel FSP is seeking a Principal Scientist I - Open Access Liquid Chromatography Chemist to work as a full-time employee on a long-term assignment onsite at a client's location in South San Francisco, California. This role involves operating, maintaining, and troubleshooting open access Waters LC-MS instruments to support discovery chemistry and high-throughput experimentation (HTE) Waters LC-MS when needed. The position requires expertise in analytical method development for characterizing various molecules, conducting purity analysis, and performing routine upkeep of LC-MS instruments. The scientist will also communicate instrument status to end-users, respond to repair calls, and maintain accurate documentation. This role is crucial for supporting the development and delivery of new therapies by providing qualified technical professionals.
Requirements
- Master’s degree in analytical chemistry or biological sciences, with at least 3 or more years of relevant and hands-on experience
- PhD in analytical chemistry or biological sciences; with 1 or more years of relevant and hands-on experience
- Reversed-phase high-performance liquid chromatography (RP-HPLC)
- Experience with Waters, Sciex, or Agilent LC-MS instrumentation and software
- High resolution mass spectrometry
- Strong communication and coordination skills
- Proficient with written and spoken English, is required
Nice To Haves
- Strong organizational skills
- Well-developed written and oral communication capabilities
Responsibilities
- Operate, maintain and troubleshoot open access Waters LC-MS instruments to support discovery chemistry, as well as HTE Waters LC-MS when needed.
- Utilizes analytical method development to characterize small molecules, peptides, antibody drug conjugates and others
- Conducts purity analysis of investigational compounds by liquid chromatography (LC)
- Checks instrument performance daily, prepares mobile phases, and performs routine upkeep of walkup liquid chromatography-mass spectrometry (LC-MS) instruments
- Communicate to end-user on status of instruments.
- Responds to end-user repair calls for LC-MS and troubleshoots/repairs simple issues such as leaks or clogs
- Submits and coordinates repair tickets for more complex issues
- Maintains accurate documentation and records
- Assist with purity analysis of investigational compounds by liquid chromatography (LC) and high-resolution mass spectrometry experiments.
- Support Laser capture microdissection (LCM) process of Open Access instruments
- LC and LC-MS analysis of small molecule samples as needed.
Benefits
- full benefits
- sick time
- 401K
- paid holidays
- paid time off
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What This Job Offers
Job Type
Full-time
Career Level
Principal
