Principal Investigator (MD/DO) - Cardiology Clinical Trials

Hawthorne Health•McAllen, TX

About The Position

Hawthorne Health is seeking an experienced Cardiology Principal Investigator (MD/DO) to lead Cardiology and Metabolic clinical trials within its community-based site network. This is a part-time, 1099 independent contractor role. The position requires on-site presence approximately 1–4 times per month for key visits, or more depending on study needs, with additional remote oversight of approximately 3–5 hours per week. The Principal Investigator oversees clinical trials at the research site, ensures participant safety and regulatory compliance, supervises the clinical research team, and makes medical decisions related to study participants. The role includes remote review of patient assessments and eligibility, review of diagnostic results, oversight of study data and investigational products, and communication with sponsors, CROs, IRBs, and regulatory authorities. Compensation is $100–$250 per hour and may be adjusted based on experience and qualifications.

Requirements

MD degree; the posting also describes the role as MD/DO, while the requirements specify MD.
Experience leading at least three sponsor-initiated trials as a PI or Sub-I.
Current, unrestricted medical license.
In-depth knowledge of ICH-GCP guidelines, FDA regulations, and other relevant ethical and regulatory requirements for clinical research.
Proven leadership and team-management skills.
Excellent clinical judgment and decision-making abilities.
Strong verbal and written communication skills in English, including the ability to present complex information clearly and concisely.
Exceptional organizational skills and meticulous attention to detail.
Ability to manage multiple complex studies simultaneously and prioritize tasks effectively.
Commitment to ethical conduct and patient safety.

Nice To Haves

Board certification in Cardiology.

Responsibilities

Accurately document findings and contribute to clinical trials, registries, or research protocols as applicable.
Oversee and manage all aspects of clinical trials conducted at the research site, ensuring adherence to study protocols, Good Clinical Practice (GCP), ICH guidelines, and applicable regulatory requirements.
Lead and supervise the clinical research team, including sub-investigators, study coordinators, and other site staff.
Delegate study-related duties to qualified personnel and ensure appropriate training and oversight.
Conduct remote reviews of patient assessments, including physical exams, medical histories, and eligibility screenings, to support appropriate participant enrollment.
Review and interpret laboratory results, ECGs, and other diagnostic tests.
Make medical decisions regarding participant care, adverse events, and protocol deviations.
Ensure accurate, complete, and timely collection and documentation of study data.
Communicate with sponsors, Contract Research Organizations (CROs), Institutional Review Boards (IRBs), and regulatory authorities.
Manage investigational product accountability, storage, and administration according to protocol, with support from the on-site IP team.
Participate in site initiation visits, monitoring visits, audits, and inspections.
Maintain continuing medical education and stay current with clinical research and relevant therapeutic-area advancements.