Principal Business Product Manager, 360 Insights

Roche • South San Francisco, CA

6d • $161,600 - $300,000 • Hybrid

About The Position

The Principal Business Product Manager leads Genentech’s 360 Insights pillar within Commercial, Medical, and Government Affairs (CMG), in the Data, Digital & Analytics organization. The role shapes customer and business insight products across CMG, bridging business strategy, user experience, data architecture, and advanced AI/ML to create enterprise analytics capabilities that support better decisions and outcomes for patients.

The position defines and executes the multi-year product vision, strategy, and roadmap for the 360 Insights portfolio, and owns the full product lifecycle from discovery and concept validation through launch, enterprise scaling, hypercare, and ongoing value realization. It partners with Roche Digital Technology, Data Science, AI/ML, Data Product, and Activation teams to guide delivery, manage dependencies, and make architectural trade-offs. The role also leads user research and prototype validation, establishes product-management practices and launch governance, and advances analytics and AI capabilities while ensuring healthcare compliance and appropriate separation of Commercial and Medical data.

This Director-level role is based in South San Francisco and follows a hybrid schedule, with three days per week on campus. Relocation benefits are not available. The expected salary range is $161,600–$300,000, with actual pay determined by experience, qualifications, geographic location, and other job-related factors. A discretionary annual bonus may be available based on individual and company performance. The position qualifies for the benefits described at the link referenced in the posting.

Requirements

• Bachelor’s degree in Business, Technology, Data Science, Analytics, Engineering, or a related quantitative field.
• At least 8 years of professional experience, including at least 5 years dedicated to pharmaceutical analytics, digital product management, or business analytics product management.

Nice To Haves

• Deep expertise in pharmaceutical commercial and healthcare data domains, such as claims, sales, access, field engagement, and patient/account affiliations.
• Proven track record managing enterprise data and analytics products through the full lifecycle, from discovery and MVP through scaling, adoption, and value measurement.
• Exceptional executive presence and stakeholder influence, including the ability to align complex cross-functional matrixed teams, navigate organizational ambiguity, and make balanced trade-off decisions.
• MBA, MS, PhD, or advanced technical degree in Analytics, Data Science, Engineering, or a related field.
• Experience delivering enterprise customer-360 architectures, decision-support tools, context/semantic layers, or AI/ML-driven analytics products.
• Hands-on product-management leadership using Jira, Jira Product Discovery, Confluence, and interactive rapid-prototyping tools.
• Advanced familiarity with generative AI capabilities, LLM integration, and modern cloud data warehouse architectures in a heavily regulated healthcare or life sciences environment.
• Prior experience leading large-scale digital transformation initiatives within a global matrixed pharmaceutical or biotech organization.

Responsibilities

• Define and execute the multi-year product vision, strategy, and roadmap for the 360 Insights portfolio, translating commercial and medical needs into scalable, reusable enterprise data and analytics capabilities.
• Own the end-to-end product lifecycle from discovery, concept validation, and MVP through launch, enterprise-wide scaling, hypercare, and continuous value realization.
• Partner with Roche Digital Technology (RDT), Data Science, AI/ML, Data Product, and Activation teams to guide technical delivery, manage dependencies, and make architectural trade-offs.
• Embed Agile product-management practices across the portfolio using Jira, Jira Product Discovery, and Confluence to provide visibility into delivery priorities and outcomes.
• Lead user research, prototype validation, and role-based UX/UI design with business champions to ensure decision-support tools are intuitive and integrated into daily workflows.
• Define business requirements, explainability standards, and human-in-the-loop oversight for advanced analytics and generative AI capabilities.
• Establish launch-readiness criteria, governance standards, and regulatory guardrails, ensuring adherence to healthcare compliance frameworks and separation of Commercial and Medical data.

Benefits

• A discretionary annual bonus may be available based on individual and company performance.
• The position qualifies for the benefits detailed at the link referenced in the posting.

What This Job Offers

• Job Type: Full-time
• Career Level: Principal