Pre-Doctoral Fellow (Chekuri)

Mass General Brigham•Boston, MA

2d•Onsite

About The Position

The Pre-Doctoral Fellow proposes and undertakes a mentored, innovative project to develop novel molecular therapies for inherited retinal degenerative diseases (IRDs). The work involves studying host-AAV interactions and retinal tropism, developing enabling gene therapy technologies, and potentially translating preclinical therapeutic gene-transfer programs. The fellow performs in vivo experiments to characterize retinal phenotypic defects in mouse models of IRDs, as well as designing and conducting in vitro and animal experiments, analyzing results, and presenting outcomes. The fellow works under the supervision of a Principal Investigator and collaborates with a research team.

Requirements

Currently enrolled in or pursuing an MD or PhD program.
Prior clinical research experience.

Responsibilities

Read, analyze, and summarize published literature.
Design and execute retrospective research studies.
Assist in executing prospective research studies.
Undertake relevant coursework if required by the mentor.
Attend relevant meetings.
Meet regularly with the mentor to review project progress and milestones.
Plan and deliver a seminar on the project.
Take on laboratory administrative responsibilities, including inventory and purchasing, when necessary.
Write a final report or submit a manuscript to a peer-reviewed journal describing the project and results.
Design and perform in vitro and animal experiments, analyze results, and present outcomes.
Perform in vivo experiments characterizing retinal phenotypic defects in mouse models of inherited retinal degenerative diseases.