Pre-Doctoral Fellow (Chekuri)

Mass General Brigham•Boston, MA

3d•$41,933 - $60,341•Onsite

About The Position

The Pre-Doctoral Fellow proposes and undertakes a mentored, innovative research project to develop novel molecular therapies for inherited retinal degenerative diseases (IRDs). The work includes studying host–AAV interactions and retinal tropism, developing enabling gene therapy technologies, and potentially translating preclinical therapeutic gene-transfer programs. The fellow performs in vivo experiments to characterize retinal phenotypic defects in mouse models of IRDs, designs and conducts in vitro and animal experiments, analyzes results, and presents findings. The fellow works under the supervision of a Principal Investigator and collaborates with a research team. The position is based in a clinic setting and may also involve remote work; the posting lists the role as onsite.

Requirements

Currently enrolled in or pursuing a doctoral degree (MD or PhD).
Prior clinical research experience.

Responsibilities

Read, analyze, and summarize published literature.
Design and execute retrospective research studies.
Assist with executing prospective research studies.
Design and perform in vitro and animal experiments, including in vivo characterization of retinal phenotypic defects in mouse models of inherited retinal degenerative diseases.
Analyze and present experimental outcomes.
Undertake relevant coursework if required by the mentor.
Attend relevant meetings.
Meet regularly with the mentor to review project progress and milestones.
Plan and deliver a seminar on the project.
Take on laboratory administrative responsibilities, such as inventory and purchasing, when necessary.
Write a final report or submit a manuscript to a peer-reviewed journal describing the project and results.