Postdoctoral Scientist Immunosafety/Toxicology

Lilly • Indianapolis, IN

1d • $58,000 - $123,200 • Onsite

About The Position

We are seeking an ambitious post-doctoral scientist with strong research and communication skills to contribute to a high-visibility research program. Your work will contribute to the development of human-relevant New Approach Methodologies (NAMs) designed to detect and predict immune-mediated drug-induced liver injury (iDILI) -a leading cause of late-stage clinical failures and drug withdrawals that current preclinical tools are largely unable to anticipate. In this role, you will:
Investigate how interactions between liver biology and the immune system contribute to drug-induced liver injury, working across hepatocyte biology, innate immune sensing, and adaptive immunity.
Help build and apply human-relevant model systems that integrate liver and immune biology into a mechanistically informed, predictive safety platform.
Contribute to a platform capable of identifying immune-mediated liver liabilities earlier in drug development, with the potential to change how the industry approaches this challenge.
Work within a collaborative, academic-style postdoctoral group that leads NAMs innovation at Lilly, with close connections across drug metabolism, computational toxicology, translational medicine, and immunogenicity functions.
Identify areas of key need across drug development and champion creative solutions to address those needs. Maintain external awareness and learning to benefit the organization.
Present findings at conferences and publish in high quality peer-reviewed journals.

Requirements

• PhD in immunology, toxicology, cell biology, pharmacology, biochemistry, or a closely related life science field (degree conferred or expected before the start date).
• Strong foundation in immunology, cell biology, or mechanistic toxicology.
• Demonstrated ability to design experiments, learn new approaches, and solve problems independently.
• Track record of peer-reviewed publications in toxicology, immunology, or liver biology, with preference for work directly relevant to DILI or immune-mediated organ toxicity.

Nice To Haves

• Self-directed and highly motivated individual who wants to learn new techniques while continually pursuing research and publication goals.
• Excellent communicator (oral and written) with presentation experience, along with a strong publication record.
• Proficient in data analysis and reporting.
• Experience with primary mammalian cell culture and in vitro model systems.
• Interest or background in liver biology, immune cell biology, antigen presentation, or drug metabolism.
• Familiarity with complex cell models, co-culture systems, or organ-on-chip approaches is a plus.
• Strong interpersonal skills and a track record of success in collaborative, multidisciplinary team environments.

Responsibilities

• Investigate how interactions between liver biology and the immune system contribute to drug-induced liver injury, working across hepatocyte biology, innate immune sensing, and adaptive immunity.
• Help build and apply human-relevant model systems that integrate liver and immune biology into a mechanistically informed, predictive safety platform.
• Contribute to a platform capable of identifying immune-mediated liver liabilities earlier in drug development, with the potential to change how the industry approaches this challenge.
• Work within a collaborative, academic-style postdoctoral group that leads NAMs innovation at Lilly, with close connections across drug metabolism, computational toxicology, translational medicine, and immunogenicity functions.
• Identify areas of key need across drug development and champion creative solutions to address those needs. Maintain external awareness and learning to benefit the organization.
• Present findings at conferences and publish in high quality peer-reviewed journals.

Benefits

• company bonus (depending, in part, on company and individual performance)
• company-sponsored 401(k)
• pension
• vacation benefits
• medical, dental, vision and prescription drug benefits
• flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
• life insurance and death benefits
• certain time off and leave of absence benefits
• well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree