Postdoctoral Scholar - Penn State Biomedical Engineering
About The Position
The Pritchard Lab in the Department of Biomedical Engineering at the Pennsylvania State University is seeking to fill a Postdoctoral Scholar position. The scholar will lead in vivo mouse studies at the interface of evolution, synthetic biology, and targeted therapy, supporting an NIH-funded program (5 year grant) that develops "selection gene drives," a regulated gene therapy that partners with standard-of-care targeted therapies to overcome drug resistance. The successful candidate will design and execute efficacy and safety studies across cell line-derived xenograft (CDX), orthotopic, patient-derived xenograft (PDX), and immune-competent syngeneic models, including intravenous vector delivery, in vivo imaging (IVIS, micro-CT), and pharmacokinetic, pharmacodynamic, and toxicology cohorts.
Requirements
- Ph.D. by the time of appointment in Biomedical Engineering or a related scientific field.
- Extensive hands-on experience with mouse tumor models.
- Extensive hands-on experience with in vivo techniques including IP, IV and SC injections, and oral gavage.
- Extensive hands-on experience with modern molecular biology.
Responsibilities
- Lead in vivo mouse studies at the interface of evolution, synthetic biology, and targeted therapy.
- Design and execute efficacy and safety studies across cell line-derived xenograft (CDX), orthotopic, patient-derived xenograft (PDX), and immune-competent syngeneic models.
- Conduct intravenous vector delivery.
- Perform in vivo imaging (IVIS, micro-CT).
- Manage pharmacokinetic, pharmacodynamic, and toxicology cohorts.
Benefits
- Competitive benefits package for full-time employees designed to support both personal and professional well-being.
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
Ph.D. or professional degree
