About The Position

A postdoctoral training position is available in the laboratory of Dr. Xinyun (Sherry) Cao, in the Microbiology Department at UT Southwestern Medical Center to study how the transcription complex regulates gene expression in bacteria. Our laboratory Cao Lab has several exciting projects related to unraveling the intricacies of RNA polymerase function and regulation within bacterial pathogens. We utilize a diverse array of methodologies in our research, including advanced techniques such as Cryo-EM, next-generation sequencing (Illumina sequencing), high-throughput screening, in vitro biochemical assays, and bacterial genetics. Candidates with projects aim to study bacterial gene and genomic regulation, the structure and function of transcription complexes, and mechanisms of transcription initiation, elongation, and termination.

Requirements

  • Ph.D. degree
  • Background in RNA biology, structural biology, bioinformatics, protein biochemistry, or bacterial genetics.

Responsibilities

  • Study how the transcription complex regulates gene expression in bacteria.
  • Unravel the intricacies of RNA polymerase function and regulation within bacterial pathogens.
  • Conduct research utilizing advanced techniques such as Cryo-EM, next-generation sequencing (Illumina sequencing), high-throughput screening, in vitro biochemical assays, and bacterial genetics.
  • Study bacterial gene and genomic regulation.
  • Investigate the structure and function of transcription complexes.
  • Explore mechanisms of transcription initiation, elongation, and termination.

Benefits

  • Postdoctoral training program
  • Benefits information available at https://www.utsouthwestern.edu/research/postdoctoral-scholars/
  • Virtual tour available at https://www.utsouthwestern.edu/research/postdoctoral-scholars/

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What This Job Offers

Job Type

Full-time

Career Level

Entry Level

Education Level

Ph.D. or professional degree

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