The Molecular Cardiology Research Institute at Tufts Medical Center is seeking a Postdoctoral Research Fellow to join Dr. Lija Swain's laboratory. The lab focuses on identifying novel therapeutic strategies for improving myocardial recovery after acute myocardial infarction and heart failure by investigating the molecular mechanisms of metabolic adaptation and mitochondrial function during myocardial ischemia/reperfusion injury. The research utilizes various in vitro and in vivo techniques, including primary cardiomyocyte isolation, mitochondrial function assays, immunohistochemistry, western blotting, flow cytometry, and hemodynamic measurements. Both large animal swine and small animal mouse models of acute myocardial infarction are employed to discover new cardioprotective pathways. The successful candidate will be a highly motivated individual with prior experience or a strong willingness to learn molecular techniques such as adult primary cardiomyocyte isolation and culture. Responsibilities will include performing and analyzing in vivo cardiac function studies in mice, working closely with the Principal Investigator on clinically relevant cardiac biology questions, independently developing protocols, establishing new methodologies, and contributing to the writing and presentation of research findings. The Molecular Cardiology Research Institute is an internationally recognized institution, and the fellow will collaborate with the PI, lab members, and other researchers within this dynamic environment.
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Job Type
Full-time
Career Level
Entry Level
Education Level
Ph.D. or professional degree