Postdoctoral Research Associate (Hillman Lab) Department of Imaging Sciences

St. Jude Children's Research Hospital•Memphis, TN

About The Position

The Hillman Lab in the newly formed Department of Imaging Sciences at St. Jude Children’s Research Hospital seeks motivated postdoctoral scientists and engineers to develop and apply advanced optical imaging and microscopy methods. The lab brings together researchers from physics, engineering, and biology in a collaborative, intellectually open environment, connecting technology development with meaningful biological insights in alignment with St. Jude’s research and clinical missions. Research areas include developing and applying high-speed 3D microscopy methods, including SCAPE/light-sheet, two-photon, fluorescence lifetime, and vibrational imaging; building large-scale and high-throughput imaging and analysis pipelines to characterize cell types and connectivity in the mammalian brain in health and disease, with extensions to spatial-omics and digital pathology; and applying wide-field optical mapping in awake, behaving mice to study brain-behavior-movement and neurovascular relationships. Work may include hypothesis-driven experimental design, data acquisition, and analysis and modeling of multidimensional datasets. Candidates with novel or complementary backgrounds and skill sets are encouraged to apply. Trainees are encouraged to pursue independent ideas while contributing to shared technical and scientific goals. The position offers support from St. Jude’s broader imaging and research infrastructure, as well as institutional resources for career development and training within a collaborative research community. Positions are available to start immediately.

Requirements

  • Doctoral-level postdoctoral scientist or engineer; a specific degree or discipline is not stated.
  • Motivation to develop and apply advanced optical imaging and microscopy methods.
  • Candidates with expertise or interest in one or more of the stated research areas are considered.

Nice To Haves

  • Background or expertise in microscopy development and applications, large-scale or high-throughput imaging and analysis, spatial-omics, digital pathology, or functional brain imaging.
  • Novel or complementary backgrounds or skill sets.

Responsibilities

  • Develop and apply advanced optical imaging and microscopy methods.
  • Design, construct, and apply high-speed 3D microscopy methods, including SCAPE/light-sheet approaches, two-photon, fluorescence lifetime, and vibrational imaging.
  • Develop and use large-scale and high-throughput imaging and analysis pipelines to characterize cell types and connectivity in the mammalian brain in health and disease.
  • Extend imaging and analysis work to high-content spatial-omics analysis and digital pathology.
  • Apply wide-field optical mapping in awake, behaving mice to study brain-behavior-movement and neurovascular relationships in health and disease.
  • Contribute to hypothesis-driven experimental design, data acquisition, and analysis and modeling of multidimensional datasets.
  • Pursue independent research ideas while contributing to shared technical and scientific goals.

Benefits

  • Access to institutional resources for career development and training.
  • Support from the broader imaging and research infrastructure at St. Jude.
  • Opportunity to work in a highly collaborative research community.
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